The applications of transition metal nanocatalysis in heterocycles synthesis

IF 3.3 3区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

Research on Chemical Intermediates Pub Date : 2026-09-05 DOI:10.1007/s11164-026-06091-z

Reshma Yadav, Pradeep Patil, Prasad Swami, Ajay Patil, Lalit Bhosale, Mayur Bharmal, Sandeep Sankpal, Shankar Hangirgekar

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Abstract

The magic of nano-based materials as catalysts has emerged as a valuable alternative in organic transformations. Recent innovations in nanocatalysis enable chemists to prepare various functionalized nanocatalysts containing metal–organic frameworks (MOFs), zeolites, graphene oxides, and different mixed metal oxides. These catalysts enhance or influence the outcome of chemical reactions compared to conventional catalytic systems. This review highlights recent advancements in nano-based catalysts and summarizes their catalytic potential in the synthesis of pharmaceutically active heterocyclic scaffolds. Furthermore, the role of supported ionic liquid nanocatalysts under environmentally benign reaction conditions is also emphasized. Lastly, the author’s perspectives are briefly discussed, including future developments in the field of nanocatalysis for eco-friendly organic transformations.

Graphical abstract

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过渡金属纳米催化在杂环化合物合成中的应用

纳米基材料作为催化剂的魔力已经在有机转化中成为一种有价值的替代品。纳米催化的最新创新使化学家能够制备各种功能化的纳米催化剂，包括金属有机框架（MOFs）、沸石、氧化石墨烯和不同的混合金属氧化物。与传统的催化系统相比，这些催化剂增强或影响化学反应的结果。本文综述了近年来纳米催化剂的研究进展，总结了纳米催化剂在合成具有药用活性的杂环支架方面的催化潜力。此外，还强调了负载型离子液体纳米催化剂在环境友好反应条件下的作用。最后，简要讨论了作者的观点，包括纳米催化生态有机转化领域的未来发展。图形抽象

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来源期刊

Research on Chemical Intermediates 化学-化学综合

CiteScore

5.70

自引率

18.20%

发文量

229

审稿时长

2.6 months

期刊介绍： Research on Chemical Intermediates publishes current research articles and concise dynamic reviews on the properties, structures and reactivities of intermediate species in all the various domains of chemistry. The journal also contains articles in related disciplines such as spectroscopy, molecular biology and biochemistry, atmospheric and environmental sciences, catalysis, photochemistry and photophysics. In addition, special issues dedicated to specific topics in the field are regularly published.