Ping Yu, Shanbin Liu, Min Li, Jie Yin, Tianrun Dai, Jinghan Mao, Yu Zhao
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引用次数: 0
Abstract
A fluorescent probe, DZM, was synthesized via a dehydration condensation reaction using 2-hydroxy-1-naphthaldehyde and 9-fluorenylmethyl carbazate as starting materials. The DZM solution exhibited a significant fluorescence enhancement (297-fold) upon the addition of Al3⁺, along with high selectivity for this ion. The calculated detection limit was as low as 0.81 nM, which was much lower than most of the values reported, demonstrating high sensitivity. The binding stoichiometry between DZM and Al3⁺ was confirmed to be 2:1 by Job's plot and 1H NMR, and the sensing mechanism was elucidated, which was further supported by Gaussian calculations confirming the presence of a photoinduced electron transfer (PET) process. Furthermore, the probe DZM was successfully employed in biological experiments and cellular fluorescence imaging.
期刊介绍：
Journal of Fluorescence is an international forum for the publication of peer-reviewed original articles that advance the practice of this established spectroscopic technique. Topics covered include advances in theory/and or data analysis, studies of the photophysics of aromatic molecules, solvent, and environmental effects, development of stationary or time-resolved measurements, advances in fluorescence microscopy, imaging, photobleaching/recovery measurements, and/or phosphorescence for studies of cell biology, chemical biology and the advanced uses of fluorescence in flow cytometry/analysis, immunology, high throughput screening/drug discovery, DNA sequencing/arrays, genomics and proteomics. Typical applications might include studies of macromolecular dynamics and conformation, intracellular chemistry, and gene expression. The journal also publishes papers that describe the synthesis and characterization of new fluorophores, particularly those displaying unique sensitivities and/or optical properties. In addition to original articles, the Journal also publishes reviews, rapid communications, short communications, letters to the editor, topical news articles, and technical and design notes.
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