Shift work, headache, and migraine in a large cohort of Dutch nurses.

IF 2.1 4区医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Annals Of Work Exposures and Health Pub Date : 2026-08-26 DOI:10.1093/annweh/wxag080

Tara van der Grinten, Sylvia H J Jochems, Flora van Leeuwen, Michael Schaapveld, Hans Kromhout, Roel Vermeulen, Jelle Vlaanderen, Susan Peters

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引用次数: 0

Abstract

Objective: Shift work is common in healthcare and may contribute to headache disorders through mechanisms such as circadian disruption and sleep disturbance. However, evidence from large prospective cohort studies remains limited. This study investigated the associations between shift work and headache and migraine in a cohort of Dutch nurses.

Methods: Participants completed questionnaires in 2011 (n = 59,768) and 2017 (n = 37,713), reporting headache, migraine, work history, sleep problems, and lifestyle factors. Headache and migraine were assessed using the validated Headache Impact Test (HIT-6) and ID-Migraine questionnaires. Associations between shift work and the prevalence of headache or migraine at baseline and follow-up were examined using Poisson regression with robust variance to directly estimate relative risks. Additional analyses examined current shift work status and shift work duration.

Results: Ever shift work was associated with a higher prevalence of headache at baseline (relative risk = 1.04, 95% confidence interval: 1.01 to 1.07), although this association attenuated after adjustment for sleep problems (relative risk = 1.01, 95% confidence interval: 0.98 to 1.04). For migraine, ever shift work was associated with a higher prevalence at follow-up (relative risk = 1.13, 95% confidence interval: 1.02 to 1.26), whereas no association was found at baseline. Current shift work was not consistently associated with headache or migraine.

Conclusions: Ever shift work was associated with a small increase in the prevalence of migraine. Associations with headache attenuated after adjustment for sleep problems. No consistent associations were observed for current shift work.

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荷兰护士轮班工作、头痛和偏头痛的研究。

目的：倒班工作在医疗保健中很常见，并可能通过昼夜节律中断和睡眠障碍等机制导致头痛疾病。然而，来自大型前瞻性队列研究的证据仍然有限。本研究调查了荷兰护士轮班工作与头痛和偏头痛之间的关系。方法：参与者分别于2011年（n = 59,768）和2017年（n = 37,713）完成问卷调查，报告头痛、偏头痛、工作史、睡眠问题和生活方式因素。使用头痛影响测试（HIT-6）和id -偏头痛问卷对头痛和偏头痛进行评估。在基线和随访时，轮班工作与头痛或偏头痛患病率之间的关系使用泊松回归进行检验，并使用稳健方差直接估计相对风险。其他分析检查了当前轮班工作状态和轮班工作持续时间。结果：在基线时，轮班工作与较高的头痛患病率相关（相对风险= 1.04,95%可信区间：1.01至1.07），尽管在调整睡眠问题后这种关联减弱（相对风险= 1.01,95%可信区间：0.98至1.04）。对于偏头痛，轮班工作与随访时较高的患病率相关（相对风险= 1.13,95%可信区间：1.02至1.26），而基线时没有发现关联。目前轮班工作并不总是与头痛或偏头痛相关。结论：轮班工作与偏头痛患病率的小幅增加有关。调整睡眠问题后，头痛的关联减弱。目前轮班工作没有观察到一致的关联。

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来源期刊

Annals Of Work Exposures and Health Medicine-Public Health, Environmental and Occupational Health

CiteScore

4.60

自引率

19.20%

发文量

期刊介绍： About the Journal Annals of Work Exposures and Health is dedicated to presenting advances in exposure science supporting the recognition, quantification, and control of exposures at work, and epidemiological studies on their effects on human health and well-being. A key question we apply to submission is, "Is this paper going to help readers better understand, quantify, and control conditions at work that adversely or positively affect health and well-being?" We are interested in high quality scientific research addressing: the quantification of work exposures, including chemical, biological, physical, biomechanical, and psychosocial, and the elements of work organization giving rise to such exposures; the relationship between these exposures and the acute and chronic health consequences for those exposed and their families and communities; populations at special risk of work-related exposures including women, under-represented minorities, immigrants, and other vulnerable groups such as temporary, contingent and informal sector workers; the effectiveness of interventions addressing exposure and risk including production technologies, work process engineering, and personal protective systems; policies and management approaches to reduce risk and improve health and well-being among workers, their families or communities; methodologies and mechanisms that underlie the quantification and/or control of exposure and risk. There is heavy pressure on space in the journal, and the above interests mean that we do not usually publish papers that simply report local conditions without generalizable results. We are also unlikely to publish reports on human health and well-being without information on the work exposure characteristics giving rise to the effects. We particularly welcome contributions from scientists based in, or addressing conditions in, developing economies that fall within the above scope.