Elemental composition of the three poisonous Digitalis L. species of Moldovan origin determined by instrumental neutron activation analysis.

IF 4.3 3区生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

Biological Trace Element Research Pub Date : 2026-09-15 DOI:10.1007/s12011-026-05346-5

Alexandru Ciocarlan, Aculina Aricu, Lidia Lungu, Inga Zinicovscaia, Dmitrii Grozdov, Nina Ciocarlan

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Abstract

Digitalis species play a significant role in the treatment of congestive heart failure and other cardiac diseases. Instrumental neutron activation analysis was employed to determine the elemental composition of three species: Digitalis ferruginea L., Digitalis lanata Ehrh., and Digitalis purpurea L. (n = 9). Analytical quality was assured using certified reference materials. Among the major elements, potassium exhibited the highest mass fractions, with values ranging from 1.52 ± 0.1% in D. purpurea to 2.79 ± 0.2% in D. ferruginea. Chlorine and iron were identified as the most abundant minor elements. Among potentially toxic elements, arsenic was detected in Digitalis ferruginea and Digitalis purpurea, whereas antimony and other elements were determiend in all species. The range of elements quantified in the present study considerably exceeds that reported in previous investigations on other Digitalis species. Notably, the mass fractions of nearly all determined elements were found to be higher in D. purpurea, which may be attributed to its biological properties and high metal uptake capacity-a finding that warrants further investigation.

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用仪器中子活化分析测定了摩尔多瓦三种有毒洋地黄的元素组成。

洋地黄在治疗充血性心力衰竭和其他心脏疾病中发挥着重要作用。采用仪器中子活化法测定了毛地黄、毛地黄三种植物的元素组成。洋地黄（n = 9）。使用经认证的标准物质保证分析质量。在主要元素中，钾的质量分数最高，在紫荆中为1.52±0.1%，在铁皮中为2.79±0.2%。氯和铁被确定为最丰富的微量元素。在潜在有毒元素中，铁地黄和紫地黄中检测到砷，而在所有物种中均检测到锑等元素。本研究中量化的元素范围大大超过以往对其他洋地黄物种的调查报告。值得注意的是，几乎所有确定的元素的质量分数都被发现在紫荆中较高，这可能归因于其生物特性和高金属吸收能力-这一发现值得进一步研究。

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来源期刊

Biological Trace Element Research 生物-内分泌学与代谢

CiteScore

8.70

自引率

10.30%

发文量

459

审稿时长

2 months

期刊介绍： Biological Trace Element Research provides a much-needed central forum for the emergent, interdisciplinary field of research on the biological, environmental, and biomedical roles of trace elements. Rather than confine itself to biochemistry, the journal emphasizes the integrative aspects of trace metal research in all appropriate fields, publishing human and animal nutritional studies devoted to the fundamental chemistry and biochemistry at issue as well as to the elucidation of the relevant aspects of preventive medicine, epidemiology, clinical chemistry, agriculture, endocrinology, animal science, pharmacology, microbiology, toxicology, virology, marine biology, sensory physiology, developmental biology, and related fields.