EXPRESSION OF CONCERN : Small Interference RNA Targeting Heat‐Shock Protein 27 Inhibits the Growth of Prostatic Cell Lines and Induces Apoptosis via Caspase‐3 Activation In Vitro

IF 4.1 2区医学 Q1 UROLOGY & NEPHROLOGY

BJU International Pub Date : 2026-09-16 DOI:10.1111/bju.70458

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引用次数: 0

Abstract

EXPRESSION OF CONCERN : P. Rocchi, P. Jugpal, A. So, S. Sinneman, S. Ettinger, L. Fazli, C. Nelson and M. Gleave, “Small Interference RNA Targeting Heat‐Shock Protein 27 Inhibits the Growth of Prostatic Cell Lines and Induces Apoptosis via Caspase‐3 Activation In Vitro ,” BJU International 98, no. 5 (2006): 1082–1089, https://doi.org/10.1111/j.1464-410X.2006.06425.x . This Expression of Concern is for the above article, published online on 09 October 2006 in Wiley Online Library ( wileyonlinelibrary.com ), and its correction https://doi.org/10.1111/bju.70026 . It has been issued by agreement between the journal Editor‐in‐Chief, Freddie Hamdy; and John Wiley & Sons Ltd. UK. The Expression of Concern has been issued following concerns raised by a third party. Following an investigation, it was confirmed that the blots in Fig. 2 were taken from earlier publications and were produced using siRNA sequences that differ from those reported in this study. As the figure does not correspond to the experimental conditions described in the study, Fig. 2 cannot be considered a valid representation of the results reported, contrary to the authors' correction. The author's institution was contacted regarding this matter, but no response has been received. As the concerns remain unresolved, the journal has decided to issue an Expression of Concern to alert readers to these issues.

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关注的表达：靶向热休克蛋白27的小干扰RNA在体外通过Caspase‐3激活抑制前列腺细胞系的生长并诱导凋亡

关注表达：P. Rocchi， P. Jugpal， A. So， S. Sinneman， S. Ettinger， L. Fazli， C. Nelson， M. Gleave，“靶向热休克蛋白27的小干扰RNA通过体外激活Caspase - 3抑制前列腺细胞系的生长和诱导凋亡”，中国生物医学工程学报，1998,no。5 (2006): 1082-1089, https://doi.org/10.1111/j.1464-410X.2006.06425.x。这篇表达关注的文章发表在2006年10月9日的Wiley在线图书馆（wileyonlinelibrary.com）上，并对其https://doi.org/10.1111/bju.70026进行了更正。它是由杂志主编Freddie Hamdy；及约翰威利父子有限公司。英国。关注表达是在第三方提出关注后发布的。经过调查，证实图2中的斑点取自早期出版物，并且使用与本研究中报道的不同的siRNA序列产生。由于该图与研究中描述的实验条件不符，因此不能认为图2是报告结果的有效表示，这与作者的更正相反。就此事联系了撰文人所在的机构，但未收到任何答复。由于这些问题仍未得到解决，该杂志决定发表一份关注表达，以提醒读者注意这些问题。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BJU International 医学-泌尿学与肾脏学

CiteScore

9.10

自引率

4.40%

发文量

262

审稿时长

1 months

期刊介绍： BJUI is one of the most highly respected medical journals in the world, with a truly international range of published papers and appeal. Every issue gives invaluable practical information in the form of original articles, reviews, comments, surgical education articles, and translational science articles in the field of urology. BJUI employs topical sections, and is in full colour, making it easier to browse or search for something specific.