Plant-mediated synthesis of ZnO nanoparticles using Rumex nepalensis extract and physicochemical characterization and biological applications

IF 1.7 3区 生物学 Q2 MULTIDISCIPLINARY SCIENCES
Abhimanyu Pawar, Kishor Naktode, Arvind Mungole, Santosh Gaikwad, Dalesh M. Parshuramkar, Chandrashekhar P. Pandhurnekar, Junaid Gulzar, Mithul V Mammen, Akhtar Rasool
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引用次数: 0

Abstract

Green synthesis has emerged as a sustainable and environmentally friendly strategy for the rapid production of nanoparticles. Zinc oxide (ZnO) nanoparticles were synthesized using Rumex nepalensis (Spreng.) leaf extract, which served as a natural reducing and stabilizing agent. This eco-friendly synthesis approach provides an alternative to conventional chemical methods by avoiding the use of toxic chemicals and minimizing environmental hazards. Structural analysis using X-ray diffraction (XRD) confirmed the formation of ZnO nanoparticles with a hexagonal wurtzite crystalline structure. Fourier-transform infrared spectroscopy (FTIR) and energy-dispersive X-ray spectroscopy (EDX) further verified the presence of Zn–O bonds and indicated a high degree of elemental purity. Morphological characterization through scanning electron microscopy (SEM) and transmission electron microscopy (TEM) revealed that the nanoparticles were mainly spherical in shape, with particle sizes ranging from approximately 11 to 13 nm. Optical analysis using UV–Visible spectroscopy showed a band gap energy of 3.26 eV, confirming the semiconducting properties of the synthesized nanoparticles. ZnO nanoparticles demonstrated significant antibacterial activity against human pathogenic bacteria, highlighting their potential as effective antimicrobial agents. The strong antioxidant activity was observed, indicating their capability to scavenge free radicals and mitigate oxidative stress, the results confirm the successful green synthesis of ZnO nanoparticles using R. nepalensis extract and emphasize their structural stability, biocompatibility, and diverse biological activities. These findings suggest promising applications of the biogenic ZnO nanoparticles in biomedical, cosmetic, and industrial fields, further supporting the role of green nanotechnology in the development of sustainable nanomaterials.

Graphical Abstract

尼泊尔芦笋提取物植物介导合成氧化锌纳米粒子及其理化性质和生物学应用。
绿色合成已经成为一种可持续和环境友好的快速生产纳米颗粒的策略。以天然还原稳定剂尼泊尔芦笋叶提取物为原料合成氧化锌纳米颗粒。这种生态友好的合成方法通过避免使用有毒化学品和最大限度地减少对环境的危害,为传统的化学方法提供了一种替代方法。x射线衍射(XRD)结构分析证实ZnO纳米颗粒具有六方纤锌矿晶体结构。傅里叶变换红外光谱(FTIR)和能量色散x射线光谱(EDX)进一步证实了Zn-O键的存在,并表明元素纯度很高。通过扫描电镜(SEM)和透射电镜(TEM)对纳米颗粒进行形貌表征,发现纳米颗粒主要为球形,粒径约为11 ~ 13 nm。紫外可见光谱的光学分析表明,所合成的纳米颗粒的能带能为3.26 eV,证实了其半导体性质。ZnO纳米颗粒对人类致病菌具有显著的抑菌活性,显示出其作为有效抗菌药物的潜力。结果表明,尼泊尔芦树提取物具有较强的抗氧化活性,具有清除自由基和减轻氧化应激的能力,为绿色合成氧化锌纳米粒子提供了有利条件,并强调了其结构稳定性、生物相容性和多种生物活性。这些发现提示了生物氧化锌纳米粒子在生物医学、化妆品和工业领域的应用前景,进一步支持了绿色纳米技术在可持续纳米材料开发中的作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
The Science of Nature
The Science of Nature 综合性期刊-综合性期刊
CiteScore
3.40
自引率
0.00%
发文量
47
审稿时长
4-8 weeks
期刊介绍: The Science of Nature - Naturwissenschaften - is Springer''s flagship multidisciplinary science journal. The journal is dedicated to the fast publication and global dissemination of high-quality research and invites papers, which are of interest to the broader community in the biological sciences. Contributions from the chemical, geological, and physical sciences are welcome if contributing to questions of general biological significance. Particularly welcomed are contributions that bridge between traditionally isolated areas and attempt to increase the conceptual understanding of systems and processes that demand an interdisciplinary approach.
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