[Association of vitiligo with endocrine autoimmune diseases: literature review].

M R Ragimov, A A Yuzbekova, A V Molochkov, I V Misnikova
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Abstract

Vitiligo is a dermatological disease characterized by focal disappearance of the melanin pigment on the skin and mucous membranes of a person. Despite the variety of proposed hypotheses for the development of this pathology, the central role belongs to the autoimmune mechanism of melanocyte damage.Analysis of the results of numerous international studies confirms a pronounced tendency towards an increase in the prevalence of endocrine autoimmune diseases among patients with vitiligo compared to the general population. Such diseases include, first of all, autoimmune thyroiditis, Graves' disease, type I diabetes mellitus and autoimmune adrenal insufficiency. Some studies confirm a high frequency of vitiligo combination with multiendocrine autoimmune syndromes.This review is aimed at systematizing the available scientific literature on the frequency of occurrence and characteristics of associated autoimmune endocrine disorders in individuals suffering from vitiligo.

[白癜风与内分泌自身免疫性疾病的关系:文献综述]。
白癜风是一种皮肤病,其特征是皮肤和粘膜上黑色素的局灶性消失。尽管对这种病理的发展提出了各种各样的假设,但核心作用属于黑素细胞损伤的自身免疫机制。对众多国际研究结果的分析证实,与一般人群相比,白癜风患者中内分泌自身免疫性疾病的患病率有明显增加的趋势。这些疾病首先包括自身免疫性甲状腺炎、格雷夫斯病、1型糖尿病和自身免疫性肾上腺功能不全。一些研究证实,白癜风合并多内分泌自身免疫性综合征的频率很高。本综述旨在系统整理现有的有关白癜风患者自身免疫性内分泌紊乱的发生频率和特征的科学文献。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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