Sex and Age Differences in Prevalence of Psychiatric Conditions Comorbid With Substance Use Disorders Among Military Veterans.

IF 1.5 4区医学 Q3 CLINICAL NEUROLOGY

Journal of Nervous and Mental Disease Pub Date : 2026-09-01 Epub Date: 2026-09-14 DOI:10.1097/NMD.0000000000001881

Reanne Cunningham Chilton, Lauren M Sippel, Lisanne van Engelen, Rani Hoff

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引用次数: 0

Abstract

Aim: Comorbid substance use disorders (SUDs) and mental health (MH) conditions pose unique challenges to veterans' functioning, quality of life, and treatment.

Methods: We characterize comorbidity between SUDs and MH conditions using a sample of 6,872,103 patients enrolled in VA health care. We queried the effect of MH conditions on comorbidity, compared sex and age groups, and characterized the impact of traumatic brain injury (TBI) using logistic regressions.

Results: Certain MH conditions are at higher risk of SUDs. There was a small but significant effect of sex and age wherein males and younger veterans were generally more likely to have a comorbid SUD. Those with TBI and TBI plus posttraumatic stress disorder had 1.80 increased odds of having an SUD.

Conclusions: Overall, results suggest that comorbid SUDs are highly prevalent among veterans with MH conditions, with some important variability in risk between subgroups that should be taken into account when developing treatment plans and novel interventions.

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退伍军人精神疾病伴物质使用障碍患病率的性别和年龄差异

目的：共病物质使用障碍（sud）和精神健康（MH）状况对退伍军人的功能、生活质量和治疗构成了独特的挑战。方法：我们使用在VA医疗保健部门登记的6,872,103例患者的样本来表征sud和MH条件之间的共病。我们询问了MH条件对合并症的影响，比较了性别和年龄组，并使用逻辑回归分析了创伤性脑损伤（TBI）的影响。结果：某些MH患者发生sud的风险较高。性别和年龄的影响虽小但很显著，其中男性和年轻的退伍军人通常更容易合并SUD。那些患有创伤性脑损伤和创伤后应激障碍的人患SUD的几率增加了1.80%。结论：总体而言，结果表明合并sud在患有MH疾病的退伍军人中非常普遍，在制定治疗计划和新的干预措施时，应考虑亚组之间风险的一些重要差异。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Nervous and Mental Disease 医学-精神病学

CiteScore

2.90

自引率

5.30%

发文量

233

审稿时长

3-8 weeks

期刊介绍： The Journal of Nervous and Mental Disease publishes peer-reviewed articles containing new data or ways of reorganizing established knowledge relevant to understanding and modifying human behavior, especially that defined as impaired or diseased, and the context, applications and effects of that knowledge. Our policy is summarized by the slogan, "Behavioral science for clinical practice." We consider articles that include at least one behavioral variable, clear definition of study populations, and replicable research designs. Authors should use the active voice and first person whenever possible.