A New Biphenyl Derivative from a Mangrove Endophytic Fungus Alternaria malorum FL39

IF 1.1 4区化学 Q4 CHEMISTRY, MEDICINAL

Chemistry of Natural Compounds Pub Date : 2026-08-07 DOI:10.1007/s10600-026-05035-8

Jinhui He, Liyi Zhang, Jiajinyu Gong, Shiheng Pan, Shenghang Zou, Wei Fan, Chunyuan Li, Yahong Xiong

引用次数: 0

Abstract

A new biphenyl derivative, 3′,4,5,5′-tetramethoxy-2-methyl-1,1′-biphenyl (1), along with the known 3′-hydroxyalternariol-5-O-methyl ether (2), 5′-methoxy-6-methylbiphenyl-2,3′,4-triol (3), and porric acid D (4) were isolated from the mangrove endophytic fungus Alternaria malorum FL39. The structure of compound 1 was deduced by analysis of comprehensive spectra. Compounds 1 and 4 exhibited moderate antifungal activities against Colletotrichum gloeosporioides. Additionally, compound 1 showed weak antifungal activity against Colletotrichum musae, whereas compounds 1–3 showed weak antibacterial activity against Escherichia coli (serotypes O6).

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红树林内生真菌褐变菌FL39的联苯新衍生物

从红树林内生真菌Alternaria malorum FL39中分离到新的联苯衍生物3 ',4,5,5 ' -四甲基-2-甲基-1,1 ' -联苯(1)，以及已知的3 ' -羟基联苯醇-5- o -甲基醚(2),5 ' -甲氧基-6-甲基联苯基-2,3 '，4-三醇(3)和porric acid D(4)。通过综合光谱分析，推导出化合物1的结构。化合物1和4对炭疽菌具有中等抑菌活性。此外，化合物1对炭疽杆菌的抑菌活性较弱，而化合物1 ~ 3对大肠杆菌（O6血清型）的抑菌活性较弱。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Chemistry of Natural Compounds 化学-有机化学

CiteScore

1.40

自引率

25.00%

发文量

265

审稿时长

7.8 months

期刊介绍： Chemistry of Natural Compounds publishes reviews and general articles about the structure of different classes of natural compounds, the chemical characteristics of botanical families, genus, and species, to establish the comparative laws and connection between physiological activity and the structure of substances.