A New Lignan from Codonopsis tangshen and Its Molecular Docking Study with Syk

IF 1.1 4区化学 Q4 CHEMISTRY, MEDICINAL

Chemistry of Natural Compounds Pub Date : 2026-08-11 DOI:10.1007/s10600-026-05038-5

Qiaoyu Yuan, Xinqiao Liu, Bei Hu, Zhengwen Wang, Runlin Xiang

引用次数: 0

Abstract

A new lignan, (7S,8R)-7′(Z)-hierochin D (1) and a known lignan, curcasinlignan B (2) were isolated from Codonopsis tangshen Oliv., The chemical structures of these compounds were identified by extensive spectroscopic analyses. Furthermore, the molecular docking results indicate that compound 1 may act as an anti-inflammatory inhibitor.

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一种新的唐参木脂素及其与Syk的分子对接研究

从党参中分离到一种新的木脂素(7S,8R)-7′(Z)-hierochin D(1)和一种已知的木脂素（curcasinlignan B(2)）。这些化合物的化学结构是通过广泛的光谱分析确定的。此外，分子对接结果表明化合物1可能具有抗炎抑制剂的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Chemistry of Natural Compounds 化学-有机化学

CiteScore

1.40

自引率

25.00%

发文量

265

审稿时长

7.8 months

期刊介绍： Chemistry of Natural Compounds publishes reviews and general articles about the structure of different classes of natural compounds, the chemical characteristics of botanical families, genus, and species, to establish the comparative laws and connection between physiological activity and the structure of substances.