Hypertension control within the HEARTS program of south-west Trinidad: a longitudinal mixed-effects analysis.

IF 1.7 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Gavaskar Ramnanansingh, Alicia Alessandra Hankey, Christopher Chang, Esther Shirley Daniel, Rajesh Lakhan
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Abstract

Objective: To describe blood pressure trajectories and hypertension control among patients enrolled in the HEARTS program in south-west Trinidad.

Methods: This retrospective longitudinal cohort study used routinely collected HEARTS program data from 31 public primary health centers in the South-West Regional Health Authority, Trinidad and Tobago. Eligible patients initiated HEARTS between 1 April and 31 October 2023, with a baseline program record and at least one follow-up blood pressure measurement. Follow-up was categorized as month-1 to month-5. McNemar's test assessed paired baseline versus month-5 control status; linear and generalized linear mixed-effects models assessed blood pressure trajectories and hypertension control.

Results: The analytic cohort included 548 patients; 63.3% were female and mean age was 61.4 ± 11.0 years. At baseline, 80.7% had uncontrolled hypertension. Mean baseline systolic blood pressure was 155 ± 22 mmHg and diastolic 86 ± 14 mmHg. Among 502 patients with paired baseline and month-5 data, more patients transitioned from uncontrolled to controlled hypertension than the reverse (70 vs 41; McNemar OR 1.71, 95% CI [1.16, 2.51], p = 0.006). In mixed-effects analyses, month was associated with lower systolic blood pressure. Odds of hypertension control were higher at month-2 and month-5 relative to baseline, while higher body mass index (BMI) was associated with lower odds of control.

Conclusions: Among patients with available follow-up data, the HEARTS program was associated with improved hypertension control in routine primary care, while higher BMI was associated with lower odds of control. These findings should be interpreted as observational program outcomes rather than evidence of a causal program effect.

特立尼达西南部HEARTS计划中的高血压控制:纵向混合效应分析。
目的:描述特立尼达西南部参加HEARTS计划的患者的血压轨迹和高血压控制。方法:这项回顾性纵向队列研究使用常规收集的来自特立尼达和多巴哥西南地区卫生局31个公共初级卫生中心的HEARTS项目数据。符合条件的患者在2023年4月1日至10月31日期间启动了HEARTS,具有基线计划记录和至少一次随访血压测量。随访时间为第1 ~第5个月。McNemar试验评估配对基线与第5个月对照状态;线性和广义线性混合效应模型评估血压轨迹和高血压控制。结果:分析队列纳入548例患者;女性占63.3%,平均年龄61.4±11.0岁。基线时,80.7%的患者高血压未得到控制。平均基线收缩压为155±22 mmHg,舒张压为86±14 mmHg。在502例基线和第5个月配对数据的患者中,从未控制到控制的高血压患者多于相反的患者(70 vs 41; McNemar OR 1.71, 95% CI [1.16, 2.51], p = 0.006)。在混合效应分析中,月龄与较低的收缩压有关。相对于基线,在第2个月和第5个月高血压控制的几率更高,而较高的体重指数(BMI)与较低的控制几率相关。结论:在可获得随访数据的患者中,HEARTS项目与常规初级保健中高血压控制的改善相关,而高BMI与较低的控制几率相关。这些发现应该被解释为观察性项目结果,而不是因果项目效应的证据。
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来源期刊
CiteScore
4.10
自引率
3.80%
发文量
222
审稿时长
20 weeks
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