A Review of Microbial Interactions and Enhancement Strategies for Medium-Chain Fatty Acids Production from Organic Wastes

IF 6.3 Q1 ENGINEERING, ENVIRONMENTAL

ACS ES&T engineering Pub Date : 2026-09-11 Epub Date: 2026-08-17 DOI:10.1021/acsestengg.6c00361

Ting Guo, Yuqing Liu, Jinlan Yu, Xinwei Li, Youpeng Chen, Mengjiao Gao

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引用次数: 0

Abstract

Medium-chain fatty acids (MCFAs) production from organic waste via microbial chain elongation (CE) technology represents a pivotal way toward high-value resource recovery. However, real organic wastes generally have complex composition, which results in intricate interspecies interactions in microbial consortium and affects MCFAs yield and process stability. Enhancing microbial cooperation and limiting competition constitute promising strategies for directing carbon flux and reducing equivalents toward the chain elongation pathway. This review provides insights into microbial interactions within real waste-fed chain elongation systems and summarizes key impact factors and recent research advances concerning the regulatory strategies for microbial cooperation. Interspecies interactions can be affected by organic waste compositions, microbial electron transfer pathways, environmental conditions, and quorum-sensing communication systems. Major optimization strategies were systematically introduced including the exogenous additions of signal molecules, supplementation of electron-transfer-mediated materials, and an advanced approach of synthetic microbial consortia. The current review aims to provide theoretical and technical support for enhancing the efficiency of MCFAs’ production from real organic wastes.

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有机废物生产中链脂肪酸的微生物相互作用及增强策略研究进展

利用微生物链延伸（CE）技术从有机废物中生产中链脂肪酸（MCFAs）是实现高价值资源回收的关键途径。然而，真正的有机废物通常具有复杂的组成，这导致微生物联合体中复杂的种间相互作用，并影响mcfa的产率和工艺稳定性。加强微生物合作和限制竞争是引导碳通量和减少链延伸途径等价物的有希望的策略。本文综述了实际垃圾供给链延伸系统中的微生物相互作用，总结了微生物合作的关键影响因素和最近的研究进展。物种间的相互作用可能受到有机废物组成、微生物电子转移途径、环境条件和群体感应通信系统的影响。系统地介绍了主要的优化策略，包括外源信号分子的添加、电子转移介导材料的补充以及合成微生物群落的先进方法。本文旨在为提高实际有机废弃物生产MCFAs的效率提供理论和技术支持。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS ES&T engineering ENGINEERING, ENVIRONMENTAL-

CiteScore

8.50

自引率

0.00%

发文量

期刊介绍： ACS ES&T Engineering publishes impactful research and review articles across all realms of environmental technology and engineering, employing a rigorous peer-review process. As a specialized journal, it aims to provide an international platform for research and innovation, inviting contributions on materials technologies, processes, data analytics, and engineering systems that can effectively manage, protect, and remediate air, water, and soil quality, as well as treat wastes and recover resources. The journal encourages research that supports informed decision-making within complex engineered systems and is grounded in mechanistic science and analytics, describing intricate environmental engineering systems. It considers papers presenting novel advancements, spanning from laboratory discovery to field-based application. However, case or demonstration studies lacking significant scientific advancements and technological innovations are not within its scope. Contributions containing experimental and/or theoretical methods, rooted in engineering principles and integrated with knowledge from other disciplines, are welcomed.