Agreement between Sirius Scheimpflug-Placido tomography and Anterion swept-source OCT in keratoconic eyes stratified by prior corneal cross-linking: a retrospective cross-sectional agreement study.

IF 1.7 4区医学 Q3 OPHTHALMOLOGY

International Ophthalmology Pub Date : 2026-09-11 DOI:10.1007/s10792-026-04227-z

Kubra Erdogan, Metin Unlu, Furkan Ozer

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Abstract

Aim: This study aims to assess the agreement between the Scheimpflug-Placido tomographer (Sirius) and the anterior-segment swept-source optical coherence tomography (Anterion) in evaluating anterior segment parameters separately in keratoconus (KC) patients with and without corneal cross-linking (CXL).

Methods: A retrospective analysis was conducted on 108 eyes of patients with keratoconus (KC), divided into two groups according to previous corneal collagen cross-linking (CXL) status: eyes with prior CXL (wCXL group, n = 72) and eyes without CXL (woCXL group, n = 36). Evaluated parameters included anterior and posterior keratometric measurements, pachymetric measurements, anterior chamber parameters, corneal astigmatism, and corneal shape/elevation-related indices. Measurements from both devices were compared using Bland-Altman analysis, assessing fixed and proportional biases. Agreement between devices was interpreted based on the combination of absence of significant fixed bias, absence of proportional bias, and the width of the 95% limits of agreement (LoA).

Results: In the wCXL group, anterior astigmatism (ant-Ast) and anterior best-fit toric ellipsoid (ant-BFT) demonstrated the most favorable bias characteristics. In the woCXL group, ant-Ast, ACD, posterior K1, and posterior Kmean showed favorable bias characteristics.

Conclusions: Although ant-Ast and ant-BFT in the wCXL group and ACD, ant-Ast, posterior K1, and posterior Kmean in the woCXL group demonstrated no statistically significant fixed or proportional bias, the relatively wide LoA do not support interchangeable use of Sirius and Anterion for these measurements.

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Sirius Scheimpflug-Placido层析成像与前角层析扫描源OCT在角膜结缔组织分层中的一致性：一项回顾性横断面一致性研究。

目的：本研究旨在评估Scheimpflug-Placido断层扫描器（Sirius）和前段扫源光学相干断层扫描器（Anterion）在分别评估有或无角膜交联（CXL）的圆锥角膜（KC）患者前段参数时的一致性。方法：对108只圆锥角膜（KC）患者进行回顾性分析，根据既往角膜胶原交联（CXL）状态分为既往有CXL的眼（wCXL组，n = 72）和无CXL的眼（woCXL组，n = 36）。评估参数包括前、后角度测量、厚测测量、前房参数、角膜散光和角膜形状/高度相关指标。使用Bland-Altman分析比较两种设备的测量结果，评估固定偏差和比例偏差。器械之间的一致性是基于无显著固定偏倚、无比例偏倚和95%一致限宽度（LoA）的组合来解释的。结果：在wCXL组中，前光散光（anti - ast）和前最佳拟合环形椭球（anti - bft）表现出最有利的偏倚特征。在woCXL组中，抗ast、ACD、后路K1和后路Kmean表现出有利的偏倚特征。结论：尽管wCXL组的抗ast和抗bft，以及woCXL组的ACD、抗ast、后路K1和后路Kmean没有统计学上显著的固定或比例偏倚，但相对较宽的LoA不支持Sirius和Anterion在这些测量中互换使用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Ophthalmology OPHTHALMOLOGY-

CiteScore

3.20

自引率

0.00%

发文量

451

期刊介绍： International Ophthalmology provides the clinician with articles on all the relevant subspecialties of ophthalmology, with a broad international scope. The emphasis is on presentation of the latest clinical research in the field. In addition, the journal includes regular sections devoted to new developments in technologies, products, and techniques.