Yan Qing, Chunxiao Chai, Kuan Li, Ye Jiang, Jingjing Li
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引用次数: 0
Abstract
MOF-based nanozymes are promising for colorimetric biosensing but are often limited by rigid coordination environments and poor active-site accessibility. Here, a 2-methylimidazole-regulated MIL-88B(Fe) nanozyme (2-MIM@MIL-88B) was prepared via an in situ coordination-competition strategy. Compared with pristine MIL-88B(Fe), 2-MIM@MIL-88B retained a spindle-like morphology but showed reduced crystallinity, nitrogen-containing species, pore-texture reorganization, and local Fe-site electronic modulation with increased defect-related centers. These changes correlated with enhanced peroxidase-like activity in the TMB-H2O2 system, despite a reduced BET surface area. In a glucose oxidase-coupled colorimetric assay, 2-MIM@MIL-88B enabled glucose detection over 0.015–0.5 mM with a detection limit of 1.7 µM.
期刊介绍：
Russian Journal of General Chemistry is a journal that covers many problems that are of general interest to the whole community of chemists. The journal is the successor to Russia’s first chemical journal, Zhurnal Russkogo Khimicheskogo Obshchestva (Journal of the Russian Chemical Society ) founded in 1869 to cover all aspects of chemistry. Now the journal is focused on the interdisciplinary areas of chemistry (organometallics, organometalloids, organoinorganic complexes, mechanochemistry, nanochemistry, etc.), new achievements and long-term results in the field. The journal publishes reviews, current scientific papers, letters to the editor, and discussion papers.
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