Multifunctional Silica-Based Optical Nanoparticles with Aqueous-Phase Multicolor Room-Temperature Phosphorescence and Structural Color

IF 8.6 1区化学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

ACS Materials Letters Pub Date : 2026-09-07 Epub Date: 2026-08-18 DOI:10.1021/acsmaterialslett.6c00594

Mingda Shan, Kongchen Wang, Kun Yang, Man Wang, Jing Du, Jiaqiang Wang, Jiayi Liang, Lihuan Tong, Su Chen, Zhongxiang Qiu, Yishan Yin, Chunlin Du, Huihui Cui, Yanwen Qi, Wenbo Wu, Ben Zhong Tang, Zhen Li

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引用次数: 0

Abstract

Developing organic−inorganic hybrid nanomaterials generating multiple optical signals remains challenging due to inherent design complexities. Herein, we present organic-SiO₂ nanohybrids exhibiting size-dependent room-temperature phosphorescence (RTP) and structural color. By employing a covalent anchoring strategy, silanized organic phosphors are incorporated into the SiO₂ matrix, protecting triplet excitons and enabling multicolor aqueous RTP emission with a maximum lifetime of 314.81 ms. Notably, as particle size increases, organic-SiO₂ RTP nanohybrids exhibit an approximately 2-fold enhancement in RTP lifetime and generate a red-shifted structural color signal through self-assembly. The long-lived luminescence and excellent biocompatibility of NPA@SiO₂ (H-120) enable in vivo afterglow imaging without additional covering treatments. Within 0.5 h after tail vein injection at an ultralow chromophore dose (0.25 mg kg⁻¹), tumor sites in mice are precisely localized via efficient cellular uptake, representing superior imaging performance. Furthermore, the unique multiplexed optical features of organic-SiO₂ nanohybrids provide significant advantages for anti-counterfeiting labeling and multi-level encryption applications.

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具有水相多色室温磷光和结构色的多功能硅基光学纳米颗粒

由于固有的设计复杂性，开发产生多光信号的有机-无机杂化纳米材料仍然具有挑战性。在此，我们提出了有机- sio2纳米杂化物，表现出与尺寸相关的室温磷光（RTP）和结构色。通过采用共价锚定策略，硅化有机荧光粉被整合到SiO2基体中，保护三重态激子，并实现多色水性RTP发射，最大寿命为314.81 ms。值得注意的是，随着粒径的增加，有机- sio2 RTP纳米杂化材料的RTP寿命增加了约2倍，并通过自组装产生了红移的结构色信号。NPA@SiO2 （H-120）的长寿命发光和优异的生物相容性使体内余辉成像无需额外的覆盖处理。在尾静脉注射超低发色团剂量（0.25 mg kg−1）后0.5小时内，通过有效的细胞摄取，小鼠肿瘤部位被精确定位，表现出优异的成像性能。此外，有机- sio2纳米杂化材料独特的多路复用光学特性为防伪标签和多级加密应用提供了显著的优势。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

ACS Materials Letters MATERIALS SCIENCE, MULTIDISCIPLINARY-

CiteScore

14.60

自引率

3.50%

发文量

261

期刊介绍： ACS Materials Letters is a journal that publishes high-quality and urgent papers at the forefront of fundamental and applied research in the field of materials science. It aims to bridge the gap between materials and other disciplines such as chemistry, engineering, and biology. The journal encourages multidisciplinary and innovative research that addresses global challenges. Papers submitted to ACS Materials Letters should clearly demonstrate the need for rapid disclosure of key results. The journal is interested in various areas including the design, synthesis, characterization, and evaluation of emerging materials, understanding the relationships between structure, property, and performance, as well as developing materials for applications in energy, environment, biomedical, electronics, and catalysis. The journal has a 2-year impact factor of 11.4 and is dedicated to publishing transformative materials research with fast processing times. The editors and staff of ACS Materials Letters actively participate in major scientific conferences and engage closely with readers and authors. The journal also maintains an active presence on social media to provide authors with greater visibility.