Zhen-Qi Liu, Vincent Bazinet, Justine Y Hansen, Filip Milisav, Andrea I Luppi, Eric G Ceballos, Asa Farahani, Laura E Suarez, Golia Shafiei, Ross D Markello, Bratislav Misic
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引用次数: 0
Abstract
Brain imaging is an increasingly interdisciplinary field, encompassing multiple data types and multiple analytic traditions. Projects typically involve many moving parts, such as building customized preprocessing pipelines, transforming between data formats, preparing datasets for analysis and, ultimately, displaying results. The field is conventionally built on highly specialized software packages that solve these individual challenges well but are not necessarily designed to be interoperable. Trainees new to the field are therefore often left to come up with isolated heuristics and workarounds to complete a project. Here we present a set of tools to navigate the increasingly complex informatics ecosystem of brain imaging. netneurotools is a Python toolkit that has been continuously developed and maintained by this laboratory's trainees. The philosophy of the toolkit is that it should be the Swiss army knife of the laboratory: functions and routines that we often use but that are not part of any established pipeline or package. Since its inception, the toolkit has been open and welcomes contributions from neuroscientists across the globe. netneurotools presents a necessary counterweight to out-of-the-box software packages and highlights the importance of smaller, ad hoc functions for implementing projects. By opening a window into the inner workings of a laboratory, netneurotools also presents an opportunity to begin a new type of discourse among groups and establish tangible links within the community.
期刊介绍:
Nature Protocols focuses on publishing protocols used to address significant biological and biomedical science research questions, including methods grounded in physics and chemistry with practical applications to biological problems. The journal caters to a primary audience of research scientists and, as such, exclusively publishes protocols with research applications. Protocols primarily aimed at influencing patient management and treatment decisions are not featured.
The specific techniques covered encompass a wide range, including but not limited to: Biochemistry, Cell biology, Cell culture, Chemical modification, Computational biology, Developmental biology, Epigenomics, Genetic analysis, Genetic modification, Genomics, Imaging, Immunology, Isolation, purification, and separation, Lipidomics, Metabolomics, Microbiology, Model organisms, Nanotechnology, Neuroscience, Nucleic-acid-based molecular biology, Pharmacology, Plant biology, Protein analysis, Proteomics, Spectroscopy, Structural biology, Synthetic chemistry, Tissue culture, Toxicology, and Virology.