Consensus expert recommendations for management of urinary dysfunction in Parkinson disease.

IF 4.3 3区 医学 Q2 CLINICAL NEUROLOGY
Delaram Safarpour, Camille P Vaughan, Kathleen E McKee, Alexandra L Tabakin, Pinky Agarwal, Aditya V Boddu, Frank C Lin, Hillary A Williams, Javier E Santiago, Jun Song, Ronald F Pfeiffer, Rohit Dhall
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引用次数: 0

Abstract

Background: Urinary symptoms may occur throughout all stages of Parkinson disease (PD) and adversely affect quality of life for patients and caregivers. Lower urinary tract symptoms are multifactorial and may include urinary urgency, frequency, nocturia, incontinence, and voiding dysfunction. These symptoms may be compounded by mobility impairment disrupt sleep and contribute to falls. An updated multidisciplinary framework is needed to integrate current evidence and evolving therapeutic options into clinical practice.

Objective: To develop consensus recommendations for screening, diagnosis, and management of urinary dysfunction in PD.

Methods: The application of a modified virtual Delphi panel allowed for the synthesis of expert opinions into clinical statements. A multidisciplinary expert panel comprising movement disorders neurologists, urologists, urogynecologists, and a geriatrician with expertise in lower urinary tract dysfunction conducted a targeted narrative review of PubMed. Draft statements were developed across four clinical domains: evaluation, PD-specific contributors, diagnostic work-up, and interventions and rehabilitation. Statements were discussed, revised, and voted on through a modified virtual Delphi process until consensus was achieved.

Results: The panel developed consensus recommendations and a unifying clinical algorithm to support screening, diagnostic evaluation, appropriate referral, and individualized multidisciplinary management.

Conclusions: These consensus recommendations provide a structured approach to evaluate and manage urinary dysfunction in PD across clinical settings.

专家对帕金森病患者泌尿功能障碍治疗的一致建议。
背景:泌尿系统症状可能出现在帕金森病(PD)的所有阶段,并对患者和护理人员的生活质量产生不利影响。下尿路症状是多因素的,可能包括尿急、尿频、夜尿、尿失禁和排尿功能障碍。这些症状可能会因行动障碍而加重,扰乱睡眠并导致跌倒。需要一个更新的多学科框架,将当前的证据和不断发展的治疗方案整合到临床实践中。目的:为PD患者泌尿功能障碍的筛查、诊断和治疗提供共识建议。方法:应用一个改进的虚拟德尔菲面板允许专家意见合成到临床陈述。一个由运动障碍神经科医生、泌尿科医生、泌尿妇科医生和具有下尿路功能障碍专业知识的老年医学专家组成的多学科专家小组对PubMed进行了有针对性的叙述性回顾。声明草案涉及四个临床领域:评估、pd特异性贡献者、诊断检查、干预和康复。通过修改后的虚拟德尔菲过程对声明进行讨论、修改和投票,直到达成共识。结果:专家组制定了一致的建议和统一的临床算法,以支持筛查、诊断评估、适当的转诊和个性化的多学科管理。结论:这些一致的建议提供了一种结构化的方法来评估和管理临床背景下PD患者的尿功能障碍。
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来源期刊
Parkinsonism & related disorders
Parkinsonism & related disorders 医学-临床神经学
CiteScore
6.20
自引率
4.90%
发文量
292
审稿时长
39 days
期刊介绍: Parkinsonism & Related Disorders publishes the results of basic and clinical research contributing to the understanding, diagnosis and treatment of all neurodegenerative syndromes in which Parkinsonism, Essential Tremor or related movement disorders may be a feature. Regular features will include: Review Articles, Point of View articles, Full-length Articles, Short Communications, Case Reports and Letter to the Editor.
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