Aranzazu Poo-López, Luis Fernández-Vega-Cueto, Belén Alfonso-Bartolozzi, Carlos Lisa, Irene Martínez-Alberquilla, David Madrid-Costa, José F Alfonso
{"title":"Long-Term follow-up of a 300° arc-length intrastromal corneal ring segment implantation in central keratoconus.","authors":"Aranzazu Poo-López, Luis Fernández-Vega-Cueto, Belén Alfonso-Bartolozzi, Carlos Lisa, Irene Martínez-Alberquilla, David Madrid-Costa, José F Alfonso","doi":"10.1177/11206721261488442","DOIUrl":null,"url":null,"abstract":"<p><p>PurposeTo evaluate the outcomes of 300° arc-length intrastromal corneal ring segment (ICRS) implantation in central keratoconus throughout a 3-year follow-up period.MethodsThis study included patients with central keratoconus who exhibited a significant increase in corneal steepness and/or prolateness and underwent 300° arc-length ICRS implantation. Uncorrected (UDVA) and corrected (CDVA) distance visual acuities, manifest refraction, keratometry, corneal asphericity at 8.0 mm and the root mean square (RMS) for coma-like aberrations for a pupil size of 4.5 mm were recorded preoperatively and at 3, 12, and 36 months postoperatively.Results131 eyes were included. All eyes were examined at 3 and 12 months postoperatively, and 94 eyes at 36 months. At three months postoperatively, UDVA (logMAR) changed from 0.85 ± 0.34 preoperatively to 0.48 ± 0.27 postoperatively (<i>p</i> < 0.0001). CDVA rose from 0.23 ± 0.14 to 0.15 ± 0.09 (<i>p</i> < 0.0001). The mean K-steep from 52.50 ± 3.42 D to 46.82 ± 2.74 D (<0.0001). The RMS for coma-like aberrations decreased from 1.45 ± 0.75 μm to 0.94 ± 0.52 μm postoperatively (<i>p</i> < 0.0001), and corneal asphericity from -1.31 ± 0.43 to -0.39 ± 0.53 (<i>p</i> < 0.0001). At 36 months, 6.4% of the eyes lost lines of CDVA compared to preoperatively, while 78.7% of the eyes gained lines of CDVA. The mean flattening in K-steep was 5.16 ± 2.17 D. 83.7% of the eyes had a postoperative K-mean ≤48.0D. The RMS for coma-like aberrations and corneal asphericity remained unchanged over the postoperative period.ConclusionA 300° arc-length ICRS implantation improved the visual acuity and induced a substantial corneal flattening over 3 years in keratoconus with a significantly high corneal steepness and/or prolateness.</p>","PeriodicalId":12000,"journal":{"name":"European Journal of Ophthalmology","volume":" ","pages":"11206721261488442"},"PeriodicalIF":1.3000,"publicationDate":"2026-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Ophthalmology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/11206721261488442","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
PurposeTo evaluate the outcomes of 300° arc-length intrastromal corneal ring segment (ICRS) implantation in central keratoconus throughout a 3-year follow-up period.MethodsThis study included patients with central keratoconus who exhibited a significant increase in corneal steepness and/or prolateness and underwent 300° arc-length ICRS implantation. Uncorrected (UDVA) and corrected (CDVA) distance visual acuities, manifest refraction, keratometry, corneal asphericity at 8.0 mm and the root mean square (RMS) for coma-like aberrations for a pupil size of 4.5 mm were recorded preoperatively and at 3, 12, and 36 months postoperatively.Results131 eyes were included. All eyes were examined at 3 and 12 months postoperatively, and 94 eyes at 36 months. At three months postoperatively, UDVA (logMAR) changed from 0.85 ± 0.34 preoperatively to 0.48 ± 0.27 postoperatively (p < 0.0001). CDVA rose from 0.23 ± 0.14 to 0.15 ± 0.09 (p < 0.0001). The mean K-steep from 52.50 ± 3.42 D to 46.82 ± 2.74 D (<0.0001). The RMS for coma-like aberrations decreased from 1.45 ± 0.75 μm to 0.94 ± 0.52 μm postoperatively (p < 0.0001), and corneal asphericity from -1.31 ± 0.43 to -0.39 ± 0.53 (p < 0.0001). At 36 months, 6.4% of the eyes lost lines of CDVA compared to preoperatively, while 78.7% of the eyes gained lines of CDVA. The mean flattening in K-steep was 5.16 ± 2.17 D. 83.7% of the eyes had a postoperative K-mean ≤48.0D. The RMS for coma-like aberrations and corneal asphericity remained unchanged over the postoperative period.ConclusionA 300° arc-length ICRS implantation improved the visual acuity and induced a substantial corneal flattening over 3 years in keratoconus with a significantly high corneal steepness and/or prolateness.
目的评价300°弧长角膜环段(ICRS)植入术在中央圆锥角膜内的3年随访效果。方法本研究纳入角膜陡度和/或扩张度明显增加的中央圆锥角膜患者,并行300°弧长ICRS植入术。术前、术后3个月、12个月和36个月分别记录未矫正(UDVA)和矫正(CDVA)距离视力、明显屈光、角膜屈光度、8.0 mm的角膜非圆度和4.5 mm瞳孔的昏迷样像差的均方根(RMS)。结果共纳入131只眼。术后3个月和12个月检查所有眼睛,36个月检查94只眼睛。术后3个月UDVA (logMAR)由术前的0.85±0.34降至术后的0.48±0.27 (p p p p
期刊介绍:
The European Journal of Ophthalmology was founded in 1991 and is issued in print bi-monthly. It publishes only peer-reviewed original research reporting clinical observations and laboratory investigations with clinical relevance focusing on new diagnostic and surgical techniques, instrument and therapy updates, results of clinical trials and research findings.