Exercise and Autonomic Cardiovascular Function—Insights From Spinal Cord-Injured Humans: A Narrative Review

IF 5.7 2区医学 Q1 PHYSIOLOGY

Acta Physiologica Pub Date : 2026-09-09 DOI:10.1111/apha.70306

Rasmus Kopp Hansen, Ryan Godsk Larsen, Tom E. Nightingale, Daniel D. Hodgkiss, Niels H. Secher, Stefanos Volianitis

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引用次数: 0

Abstract

The cardiovascular response to acute exercise is mediated by the autonomic nervous system (ANS) control mechanisms that modulate vascular resistance to support blood pressure and ensure adequate blood flow to active muscles. These autonomic neurocirculatory control mechanisms include a feedforward mechanism, known as central command, and three feedback mechanisms, namely, (1) the exercise pressor reflex, (2) the baroreflex, and (3) the arterial chemoreflex. The purpose of this narrative review is to present the alterations in autonomic cardiovascular function during dynamic exercise with insights from individuals living with spinal cord injury (SCI). To fully appreciate these alterations, we first provide a general overview of ANS control of cardiovascular responses to exercise in non-injured individuals with intact supraspinal control, followed by an overview of the acute cardiovascular response to exercise in individuals with SCI. We also review the impact of exercise interventions in individuals with SCI on autonomic cardiovascular control and cardiac and vascular adaptations.

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运动和自主心血管功能的见解从脊髓损伤的人：叙述回顾。

心血管对急性运动的反应是由自主神经系统（ANS）控制机制介导的，该机制调节血管阻力以支持血压并确保足够的血液流向活动肌肉。这些自主神经循环控制机制包括一种前馈机制，即中央指令，以及三种反馈机制，即(1)运动加压反射，(2)压力反射和(3)动脉化学反射。这篇叙述性综述的目的是介绍动态运动中自主心血管功能的改变，以及脊髓损伤（SCI）患者的见解。为了充分了解这些变化，我们首先概述了脊柱上控制完整的非损伤个体对运动的心血管反应的ANS控制，然后概述了脊髓损伤个体对运动的急性心血管反应。我们还回顾了运动干预对脊髓损伤患者自主心血管控制和心脏血管适应性的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta Physiologica 医学-生理学

CiteScore

11.80

自引率

15.90%

发文量

182

审稿时长

4-8 weeks

期刊介绍： Acta Physiologica is an important forum for the publication of high quality original research in physiology and related areas by authors from all over the world. Acta Physiologica is a leading journal in human/translational physiology while promoting all aspects of the science of physiology. The journal publishes full length original articles on important new observations as well as reviews and commentaries.