Xiaoyan Si, Xiaomin Wei, Xiaoyan Liu, Mei Li, Mengzhao Wang, Li Zhang
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引用次数: 0
Abstract
Anemia is prevalent in patients with cancer, and anemia of inflammation (AI) is a common pathophysiological type. AI is mainly characterized by functional iron deficiency. This review summarizes the current knowledge regarding the epidemiology, clinical manifestations, molecular mechanisms, diagnostic criteria, and therapeutic advancements in cancer-related AI. It focuses on the central role of interleukin-6 (IL-6) and the emerging therapeutic strategies targeting the IL-6-hepcidin-ferroportin axis. Additionally, this review integrates practical educational content designed for oncologists and nurses to enhance their clinical competence in recognizing, diagnosing, and managing AI; it is essential to alleviate the symptom burden and improve the quality of life of patients with cancer.
期刊介绍：
Thoracic Cancer aims to facilitate international collaboration and exchange of comprehensive and cutting-edge information on basic, translational, and applied clinical research in lung cancer, esophageal cancer, mediastinal cancer, breast cancer and other thoracic malignancies. Prevention, treatment and research relevant to Asia-Pacific is a focus area, but submissions from all regions are welcomed. The editors encourage contributions relevant to prevention, general thoracic surgery, medical oncology, radiology, radiation medicine, pathology, basic cancer research, as well as epidemiological and translational studies in thoracic cancer. Thoracic Cancer is the official publication of the Chinese Society of Lung Cancer, International Chinese Society of Thoracic Surgery and is endorsed by the Korean Association for the Study of Lung Cancer and the Hong Kong Cancer Therapy Society.
The Journal publishes a range of article types including: Editorials, Invited Reviews, Mini Reviews, Original Articles, Clinical Guidelines, Technological Notes, Imaging in thoracic cancer, Meeting Reports, Case Reports, Letters to the Editor, Commentaries, and Brief Reports.
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