Aprilgate Wang, Samuel Ji, Sarah Semon, Sarah Waldman, Minh-Vu H Nguyen
{"title":"Reactivation of <i>Cytomegalovirus</i> in Colonic Tuberculosis in an Immunocompetent Patient.","authors":"Aprilgate Wang, Samuel Ji, Sarah Semon, Sarah Waldman, Minh-Vu H Nguyen","doi":"10.1155/crdi/5455768","DOIUrl":null,"url":null,"abstract":"<p><p><i>Cytomegalovirus</i> (CMV) reactivation in <i>Mycobacterium tuberculosis</i> (TB) infection is rare and has been only reported in immunocompromised patients. In this case report, we describe a patient with Type 2 diabetes with acute on chronic abdominal pain found to have miliary TB with terminal ileitis and ascending colon ulcers with biopsy-positive TB and CMV. The decision was made not to treat the local CMV reactivation, and he improved solely on standard drug-susceptible antituberculous therapy. This is the first reported case of gastrointestinal TB and CMV coinfection in a patient without known classic immunodeficiency.</p>","PeriodicalId":9608,"journal":{"name":"Case Reports in Infectious Diseases","volume":"2026 ","pages":"5455768"},"PeriodicalIF":0.8000,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13551487/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Case Reports in Infectious Diseases","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/crdi/5455768","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
引用次数: 0
Abstract
Cytomegalovirus (CMV) reactivation in Mycobacterium tuberculosis (TB) infection is rare and has been only reported in immunocompromised patients. In this case report, we describe a patient with Type 2 diabetes with acute on chronic abdominal pain found to have miliary TB with terminal ileitis and ascending colon ulcers with biopsy-positive TB and CMV. The decision was made not to treat the local CMV reactivation, and he improved solely on standard drug-susceptible antituberculous therapy. This is the first reported case of gastrointestinal TB and CMV coinfection in a patient without known classic immunodeficiency.