Skeletal muscle stem cells keep their lineage options open

IF 9.2 1区生物学 Q1 CELL BIOLOGY

Developmental cell Pub Date : 2026-09-09 DOI:10.1016/j.devcel.2026.08.009

Vittorio Sartorelli

引用次数: 0

Abstract

Expression of Pax7 has been widely used as a hallmark of muscle stem cell identity, and genetic deletion of Pax7 compromises skeletal muscle regeneration. In this issue of Developmental Cell, Gioftsidi, Hayashi et al. use lineage-tracing approaches to report that other skeletal muscle cell types also express Pax7.1

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骨骼肌干细胞保持其谱系选择的开放性

Pax7的表达已被广泛用作肌肉干细胞身份的标志，Pax7的基因缺失会损害骨骼肌的再生。在本期《发育细胞》中，Gioftsidi、Hayashi等人使用谱系追踪方法报道了其他骨骼肌细胞类型也表达Pax7.1

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Developmental cell 生物-发育生物学

CiteScore

18.90

自引率

1.70%

发文量

203

审稿时长

3-6 weeks

期刊介绍： Developmental Cell, established in 2001, is a comprehensive journal that explores a wide range of topics in cell and developmental biology. Our publication encompasses work across various disciplines within biology, with a particular emphasis on investigating the intersections between cell biology, developmental biology, and other related fields. Our primary objective is to present research conducted through a cell biological perspective, addressing the essential mechanisms governing cell function, cellular interactions, and responses to the environment. Moreover, we focus on understanding the collective behavior of cells, culminating in the formation of tissues, organs, and whole organisms, while also investigating the consequences of any malfunctions in these intricate processes.