A Hippo-thesis: Can bacteria turn back reproductive time?

IF 23.2 1区医学 Q1 MICROBIOLOGY

Cell host & microbe Pub Date : 2026-09-09 DOI:10.1016/j.chom.2026.08.012

Caroline M. Mitchell

引用次数: 0

Abstract

Fertility declines with age, partly because the endometrium ages alongside the oocyte. In this issue, Li et al. show that Lactobacillus gasseri and its exopolysaccharide reduce endometrial senescence and improve implantation in aged mice. Although senescence markers responded similarly in human endometrial cells, effects on human pregnancy rates remain unclear.

查看原文本刊更多论文

河马论文：细菌能逆转繁殖时间吗？

生育能力随着年龄的增长而下降，部分原因是子宫内膜随着卵母细胞的衰老而衰老。Li等在本期研究中发现，乳杆菌及其胞外多糖可减少老龄小鼠子宫内膜衰老，改善着床。虽然衰老标志物在人类子宫内膜细胞中有类似的反应，但对人类怀孕率的影响仍不清楚。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Cell host & microbe 生物-微生物学

CiteScore

45.10

自引率

1.70%

发文量

201

审稿时长

4-8 weeks

期刊介绍： Cell Host & Microbe is a scientific journal that was launched in March 2007. The journal aims to provide a platform for scientists to exchange ideas and concepts related to the study of microbes and their interaction with host organisms at a molecular, cellular, and immune level. It publishes novel findings on a wide range of microorganisms including bacteria, fungi, parasites, and viruses. The journal focuses on the interface between the microbe and its host, whether the host is a vertebrate, invertebrate, or plant, and whether the microbe is pathogenic, non-pathogenic, or commensal. The integrated study of microbes and their interactions with each other, their host, and the cellular environment they inhabit is a unifying theme of the journal. The published work in Cell Host & Microbe is expected to be of exceptional significance within its field and also of interest to researchers in other areas. In addition to primary research articles, the journal features expert analysis, commentary, and reviews on current topics of interest in the field.