C7 Vertebral Pathological Compressive Fracture after Radiotherapy for Esophageal Cancer: A Case Report.

NMC case report journal Pub Date : 2026-08-14 eCollection Date: 2026-01-01 DOI:10.2176/jns-nmc.2025-0426
Keiichiro Furuta, Hisaaki Uchikado, Gohsuke Hattori, Takahisa Nonaka, Satoru Komaki, Takehiro Makizono, Motohiro Morioka
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Abstract

Vertebral compression fractures (VCF) after radiation therapy (RT) are uncommon, particularly in the mid- and lower cervical spine. Surgical management of symptomatic cases can be challenging. Here, we report the case of a 63-year-old woman with radiculomyelopathy and C7 VCF. The patient presented with neck pain and bilateral hand numbness without osteoporosis. Four years previously, she had been cured of esophageal cancer through endoscopic surgery and RT without chemotherapy. Imaging revealed a pathological C7 vertebral body fracture with kyphotic deformity. Symptomatic VCF was diagnosed. Because of concerns regarding complications with an anterior approach, posterior-only decompression and fixation were performed. Intraoperative biopsy at C7 vertebra confirmed a diagnosis of avascular necrosis without metastasis. Fixation was performed by inserting lateral mass screw at C5-, 6 and pedicle screw at T1-, 2, connected by a rod. A multipoint screw was used to enhance rostral stability. The symptoms were alleviated postoperatively, and the patient remained well at 2-year follow-up.

食管癌放疗后C7椎体病理性压缩性骨折1例。
放射治疗(RT)后椎体压缩性骨折(VCF)并不常见,特别是在中、下颈椎。有症状病例的外科治疗具有挑战性。在这里,我们报告一例63岁女性神经根性脊髓病和C7 VCF。患者表现为颈部疼痛,双侧手部麻木,无骨质疏松。四年前,她通过内窥镜手术和放疗治愈了食管癌,没有化疗。影像学显示病理性C7椎体骨折伴后凸畸形。诊断为症状性VCF。由于担心前路手术的并发症,我们只进行了后路减压和固定。术中C7椎体活检证实诊断为无转移的缺血性坏死。通过插入C5-、6位侧块螺钉和T1-、2位椎弓根螺钉,通过一根棒连接进行固定。采用多点螺钉增强吻侧稳定性。术后症状减轻,随访2年,病情保持良好。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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