[Bullous eruption in the elderly - a case report with diagnostic challenges].

Q4 Medicine
Praxis Pub Date : 2026-08-01 DOI:10.23785/PRAXIS.2026.08.005
Clara Petroff, Reinhard Dummer, Rebecca Galalae
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引用次数: 0

Abstract

Introduction: We report the case of an 88-year-old female patient presenting with progressive, severely pruritic skin lesions and scattered blisters on the trunk and extremities. Histological examination revealed subepidermal blister formation with a neutrophil-rich infiltrate. Differentiation from other autoimmune blistering diseases was initially challenging. The diagnosis was ultimately guided by the linear IgA deposition pattern along the dermoepidermal junction on direct immunofluorescence. This case highlights the diagnostic difficulties of this rare condition and the rapid clinical improvement following appropriate therapy.

[老年人大疱性爆发——一例诊断上的挑战]。
我们报告一例88岁的女性患者,表现为进行性,严重瘙痒性皮肤病变和躯干和四肢分散的水疱。组织学检查显示皮下水疱形成,并有中性粒细胞浸润。与其他自身免疫性水疱疾病的鉴别最初是具有挑战性的。在直接免疫荧光上,IgA沿着真皮表皮连接处呈线性沉积模式,最终指导诊断。这个病例突出了这种罕见疾病的诊断困难和经过适当治疗后的快速临床改善。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Praxis
Praxis Medicine-Medicine (all)
CiteScore
0.40
自引率
0.00%
发文量
146
审稿时长
12 weeks
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