Ali Zare Dehnavi, Jorge Patino, Kendra M Anderson, Ineke Olsthoorn, Natalia Pessoa Rocha, Erin Furr Stimming
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引用次数: 0
Abstract
Delusional infestation (DI) is an uncommon manifestation of psychosis in Parkinson disease (PD), and is often associated with dopaminergic therapy. We describe a 66-year-old woman with PD who developed visual and tactile delusions of a parasitic infestation while receiving dopaminergic medications. Comprehensive neuropsychological testing revealed largely preserved cognitive functioning, with only mild relative weaknesses in processing speed and problem-solving. The patient's symptoms resolved following discontinuation of amantadine, supporting an iatrogenic etiology. Previous case reports have consistently described a link between DI and dopaminergic overstimulation, although DI has been observed across a broad range of cognitive functioning. This case highlights the diagnostic utility of formal neuropsychological assessment and underscores the importance of recognizing DI as a potentially reversible, iatrogenic phenomenon within the spectrum of PD psychosis.
期刊介绍：
Neurocase is a rapid response journal of case studies and innovative group studies in neuropsychology, neuropsychiatry and behavioral neurology that speak to the neural basis of cognition. Four types of manuscript are considered for publication: single case investigations that bear directly on issues of relevance to theoretical issues or brain-behavior relationships; group studies of subjects with brain dysfunction that address issues relevant to the understanding of human cognition; reviews of important topics in the domains of neuropsychology, neuropsychiatry and behavioral neurology; and brief reports (up to 2500 words) that replicate previous reports dealing with issues of considerable significance. Of particular interest are investigations that include precise anatomical localization of lesions or neural activity via imaging or other techniques, as well as studies of patients with neurodegenerative diseases, since these diseases are becoming more common as our population ages. Topic reviews are included in most issues.
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