Rare pediatric coexistence of combined hamartoma of the retina and retinal pigment epithelium and Coats' disease: Clinical course, imaging, and management.

IF 1 4区医学 Q3 OPHTHALMOLOGY

Journal Francais D Ophtalmologie Pub Date : 2026-09-04 DOI:10.1016/j.jfo.2026.104963

B Azarkan, R El Hachimi, Z Hilali, L Sbai, S Benchekroun, A Amazouzi, N Boutimzine, L O Cherkaoui

{"title":"Rare pediatric coexistence of combined hamartoma of the retina and retinal pigment epithelium and Coats' disease: Clinical course, imaging, and management.","authors":"B Azarkan, R El Hachimi, Z Hilali, L Sbai, S Benchekroun, A Amazouzi, N Boutimzine, L O Cherkaoui","doi":"10.1016/j.jfo.2026.104963","DOIUrl":null,"url":null,"abstract":"Purpose: To report a rare pediatric case of juxtapapillary combined hamartoma of the retina and retinal pigment epithelium (CHRRPE) with superimposed peripheral Coats lesions, highlighting multimodal imaging and stepwise management.Methods: A 10-year-old boy with CHRRPE and peripheral Coats lesions was managed with targeted laser photocoagulation, followed by intravitreal anti-VEGF injection for persistent exudation. Multimodal imaging, including OCT, OCTA, and fluorescein angiography, guided diagnosis and treatment.Results: Two-year follow-up demonstrated stable retinal lesions, preserved visual function, and absence of vitreoretinal traction or neovascular glaucoma. Multimodal imaging allowed differentiation of overlapping lesions and guided selective intervention.Conclusion: This case illustrates the importance of individualized, stepwise management in complex pediatric retinal disorders and the critical role of multimodal imaging in guiding treatment.","PeriodicalId":14777,"journal":{"name":"Journal Francais D Ophtalmologie","volume":"49 8","pages":"104963"},"PeriodicalIF":1.0000,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal Francais D Ophtalmologie","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.jfo.2026.104963","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose: To report a rare pediatric case of juxtapapillary combined hamartoma of the retina and retinal pigment epithelium (CHRRPE) with superimposed peripheral Coats lesions, highlighting multimodal imaging and stepwise management.

Methods: A 10-year-old boy with CHRRPE and peripheral Coats lesions was managed with targeted laser photocoagulation, followed by intravitreal anti-VEGF injection for persistent exudation. Multimodal imaging, including OCT, OCTA, and fluorescein angiography, guided diagnosis and treatment.

Results: Two-year follow-up demonstrated stable retinal lesions, preserved visual function, and absence of vitreoretinal traction or neovascular glaucoma. Multimodal imaging allowed differentiation of overlapping lesions and guided selective intervention.

Conclusion: This case illustrates the importance of individualized, stepwise management in complex pediatric retinal disorders and the critical role of multimodal imaging in guiding treatment.

查看原文本刊更多论文

罕见的儿童视网膜和视网膜色素上皮合并错构瘤与Coats病共存：临床病程、影像学和治疗

目的：报告一例罕见的儿童视网膜和视网膜色素上皮并乳头状合并错构瘤（CHRRPE）合并周围Coats病变，强调多模式成像和逐步治疗。方法：1例10岁男孩CHRRPE伴周围Coats病变，采用激光靶向光凝治疗，玻璃体内注射抗vegf治疗持续渗出。多模式成像，包括OCT、OCTA和荧光素血管造影，指导诊断和治疗。结果：两年随访显示视网膜病变稳定，视觉功能保存，无玻璃体视网膜牵拉或新生血管性青光眼。多模态成像可以区分重叠病变并指导选择性干预。结论：本病例说明了在复杂的儿童视网膜疾病中个体化、分步治疗的重要性，以及多模态成像在指导治疗中的关键作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal Francais D Ophtalmologie 医学-眼科学

CiteScore

1.10

自引率

8.30%

发文量

317

审稿时长

49 days

期刊介绍： The Journal français d''ophtalmologie, official publication of the French Society of Ophthalmology, serves the French Speaking Community by publishing excellent research articles, communications of the French Society of Ophthalmology, in-depth reviews, position papers, letters received by the editor and a rich image bank in each issue. The scientific quality is guaranteed through unbiased peer-review, and the journal is member of the Committee of Publication Ethics (COPE). The editors strongly discourage editorial misconduct and in particular if duplicative text from published sources is identified without proper citation, the submission will not be considered for peer review and returned to the authors or immediately rejected.