Joey Liang, Justin L Anderson, Jackson M Cathey, Justin Zhang, Victoria N Yi, Ash Patel
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引用次数: 0
Abstract
Background: While pharmacologic weight loss therapies like glucagon-like peptide-1 receptor agonists (GLP-1RAs) have increased in popularity, body contouring patients' utilization of other weight loss modalities remains unclear.
Objectives: This retrospective cohort study examined the weight loss modalities used by body contouring patients and their impacts on procedure choice and surgical outcomes.
Setting: University Hospital, United States.
Methods: The TriNetX Research Network was queried for patients who received abdominoplasties, panniculectomies, thighplasties, and brachioplasties between 2012 and 2024. The incidence and prevalence of weight loss modalities were extracted. Trends in weight loss modality utilization were evaluated by Mann-Kendall test.
Results: A total of 27,443 body contouring patients were included. Bariatric surgery (15.86%) was the most prevalent weight loss modality. Bariatric surgery (τ = .87, P < .001), naltrexone (τ = .87, P < .001), phentermine (τ = .82, P = .001), and liraglutide (τ = .78, P = .002) demonstrated the strongest increases in utilization overall. Subgroup analysis demonstrated increasing utilization of semaglutide among GLP-1RA users and increasing utilization of sleeve gastrectomy and gastric bypass among bariatric surgery recipients. Patients utilizing bariatric surgery (95.86% vs 92.62%, P < .001) and phentermine (94.29% vs 92.62%, P = .009) had significantly higher rates of abdominal contouring than non-medical weight loss controls. Bariatric surgery recipients also had lower rates of extremity contouring than controls (7.67% vs 9.31%, P = .003).
Conclusions: Body contouring patients utilize a variety of surgical and pharmacologic weight loss modalities. Patients using potent weight loss modalities may more frequently undergo abdominal contouring compared to extremity contouring, potentially due to preferential abdominal skin laxity from massive weight loss.
背景：虽然胰高血糖素样肽-1受体激动剂（GLP-1RAs）等药物减肥疗法越来越受欢迎，但身体轮廓患者使用其他减肥方式仍不清楚。目的：本回顾性队列研究探讨了身体轮廓患者使用的减肥方式及其对手术选择和手术结果的影响。地点：美国大学医院。方法：通过TriNetX研究网络查询2012年至2024年间接受腹部整形、胰腺切除术、股骨整形和肱成形术的患者。提取减肥方式的发生率和流行率。采用Mann-Kendall检验评估减肥方式使用的趋势。结果：共纳入27443例体塑形患者。减肥手术（15.86%）是最普遍的减肥方式。减肥手术（τ = .87, P < .001）、纳曲酮（τ = .87, P < .001）、芬特明（τ = .82, P = .001）和利拉鲁肽（τ = .78, P = .002）的总体利用率增长最为明显。亚组分析显示，在GLP-1RA使用者中，semaglutide的使用率越来越高，在减肥手术接受者中，袖式胃切除术和胃旁路术的使用率越来越高。使用减肥手术（95.86% vs 92.62%, P < 0.001）和芬特明（94.29% vs 92.62%, P = 0.009）的患者腹部轮廓率明显高于非药物减肥对照组。减肥手术接受者的肢体轮廓率也低于对照组（7.67% vs 9.31%, P = 0.003）。结论：身体轮廓患者使用各种手术和药物减肥方式。使用有效减肥方式的患者可能更频繁地进行腹部轮廓术，而不是四肢轮廓术，这可能是由于大量减肥导致腹部皮肤松弛。
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