Generation of human induced pluripotent stem cell line, NIMHi034-A, from peripheral blood mononuclear cells of a healthy Indian adult male

IF 0.6 4区医学 Q4 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

Stem cell research Pub Date : 2026-09-01 Epub Date: 2026-08-28 DOI:10.1016/j.scr.2026.104093

V. Ramya, Lekshmi Krishna, Trichur R. Raju, Talakad N. Sathyaprabha, K. Vijayalakshmi

引用次数: 0

Abstract

Induced pluripotent stem cell (iPSCs) line, NIMHi034-A has been generated from peripheral blood mononuclear cells (PBMCs) of a 59-year-old healthy Indian adult male using non-integrating Sendai viral reprogramming vectors in a feeder free method. The iPSCs exhibit normal karyotype, express markers of undifferentiated state and could differentiate in-vitro into cells of three germ layers. This cell line can serve as a healthy control for various disease models and in deciphering disease mechanisms.

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从印度健康成年男性外周血单个核细胞制备人诱导多能干细胞系NIMHi034-A。

NIMHi034-A诱导多能干细胞系（iPSCs）采用仙台病毒重编程载体，以59岁印度健康成年男性外周血单个核细胞（PBMCs）为载体，采用无喂虫方法制备。iPSCs核型正常，表达未分化状态的标记物，在体外可分化为三种胚层细胞。该细胞系可作为多种疾病模型的健康对照，并可用于破译疾病机制。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Stem cell research 生物-生物工程与应用微生物

CiteScore

2.20

自引率

8.30%

发文量

338

审稿时长

55 days

期刊介绍： Stem Cell Research is dedicated to publishing high-quality manuscripts focusing on the biology and applications of stem cell research. Submissions to Stem Cell Research, may cover all aspects of stem cells, including embryonic stem cells, tissue-specific stem cells, cancer stem cells, developmental studies, stem cell genomes, and translational research. Stem Cell Research publishes 6 issues a year.