Gintonin protects hematopoietic stem cells and accelerates bone marrow recovery following cyclophosphamide-induced injury

IF 7.5 2区医学 Q1 CHEMISTRY, MEDICINAL

Journal of Ginseng Research Pub Date : 2026-09-01 Epub Date: 2026-07-07 DOI:10.1016/j.jgr.2026.101109

Ajay Vijayakumar, BaiCheng Chen, Jun Hong Park, Seung-Yeol Nah, Jong-Hoon Kim

引用次数: 0

Abstract

Gintonin administration to mice with hematopoietic injury induced by cyclophosphamide (CY) demonstrated that, gintonin promotes hematopoietic recovery as evidenced by restored count of blood cells, alleviated bone marrow suppression and reduced apoptosis of hematopoietic stem cells indicating the potential of gintonin as an adjunct therapeutic agent in chemotherapy.

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银杏苷保护造血干细胞和加速骨髓恢复后，环磷酰胺诱导损伤

对环磷酰胺（CY）诱导的造血损伤小鼠给予银tonin，结果表明，银tonin促进造血功能恢复，血细胞计数恢复，骨髓抑制减轻，造血干细胞凋亡减少，表明银tonin有可能作为化疗辅助治疗剂。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Ginseng Research CHEMISTRY, MEDICINAL-INTEGRATIVE & COMPLEMENTARY MEDICINE

CiteScore

11.40

自引率

9.50%

发文量

111

审稿时长

6-12 weeks

期刊介绍： Journal of Ginseng Research (JGR) is an official, open access journal of the Korean Society of Ginseng and is the only international journal publishing scholarly reports on ginseng research in the world. The journal is a bimonthly peer-reviewed publication featuring high-quality studies related to basic, pre-clinical, and clinical researches on ginseng to reflect recent progresses in ginseng research. JGR publishes papers, either experimental or theoretical, that advance our understanding of ginseng science, including plant sciences, biology, chemistry, pharmacology, toxicology, pharmacokinetics, veterinary medicine, biochemistry, manufacture, and clinical study of ginseng since 1976. It also includes the new paradigm of integrative research, covering alternative medicinal approaches. Article types considered for publication include review articles, original research articles, and brief reports. JGR helps researchers to understand mechanisms for traditional efficacy of ginseng and to put their clinical evidence together. It provides balanced information on basic science and clinical applications to researchers, manufacturers, practitioners, teachers, scholars, and medical doctors.