Adenocarcinoma of the Rete Testis With PI3K/AKT/mTOR Pathway Alteration and a Gene Expression Profile Resembling Papillary Renal Cell Carcinoma: A Case Report.
Sachein Sharma, Ryan Jaehne, Cyrus Oster, Dong Ren, Shivani Kandukuri, Li Lei, Dimitrios Korentzelos, Matthew J Oberley, Eugene Muchnik, Mark G Evans
{"title":"Adenocarcinoma of the Rete Testis With PI3K/AKT/mTOR Pathway Alteration and a Gene Expression Profile Resembling Papillary Renal Cell Carcinoma: A Case Report.","authors":"Sachein Sharma, Ryan Jaehne, Cyrus Oster, Dong Ren, Shivani Kandukuri, Li Lei, Dimitrios Korentzelos, Matthew J Oberley, Eugene Muchnik, Mark G Evans","doi":"10.1155/criu/8508136","DOIUrl":null,"url":null,"abstract":"<p><p>Adenocarcinoma of the rete testis (ACRT) is a rare, gland-forming neoplasm arising from rete testis epithelium and is typically associated with poor prognosis. Currently, our knowledge of ACRT has been limited to single reports and small series, and its molecular characteristics are largely unknown. We present a patient, whose scrotal tumor demonstrated a gene expression profile similar to that of papillary renal cell carcinoma (PRCC) and alteration of PI3K/AKT/mTOR pathway, thereby expanding our understanding of the genomic landscape of ACRT.</p>","PeriodicalId":30323,"journal":{"name":"Case Reports in Urology","volume":"2026 ","pages":"8508136"},"PeriodicalIF":0.0000,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13504671/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Case Reports in Urology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1155/criu/8508136","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Adenocarcinoma of the rete testis (ACRT) is a rare, gland-forming neoplasm arising from rete testis epithelium and is typically associated with poor prognosis. Currently, our knowledge of ACRT has been limited to single reports and small series, and its molecular characteristics are largely unknown. We present a patient, whose scrotal tumor demonstrated a gene expression profile similar to that of papillary renal cell carcinoma (PRCC) and alteration of PI3K/AKT/mTOR pathway, thereby expanding our understanding of the genomic landscape of ACRT.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
