M. M. Ivanova, K. V. Stepanova, A. A. Vasilyeva, M. V. Matiash, V. V. Apyari, S. V. Maksimov, S. G. Dmitrienko
{"title":"Luminescence–Colorimetric Determination of Adrenaline Using Carbon Nanodots","authors":"M. M. Ivanova, K. V. Stepanova, A. A. Vasilyeva, M. V. Matiash, V. V. Apyari, S. V. Maksimov, S. G. Dmitrienko","doi":"10.1134/S1061934826700681","DOIUrl":null,"url":null,"abstract":"<p>Carbon nanodots (<b>CND</b>s) of an average size of 2.7 ± 0.1 nm, exhibiting intense luminescence at 465 nm upon irradiation with a wavelength of 365 nm were synthesized from citric acid using the pyrolytic method. It was shown that, in the presence of the oxidized form of adrenaline, absorbing light at 365 nm, a noticeable quenching of the luminescence of CNDs was observed, which can be used for the luminescence determination of adrenaline. As CNDs are characterized by luminescence in the visible spectral region, both visual and colorimetric (using a camera and a smartphone camera) determination of adrenaline is possible; the achieved limit of detection is 0.8 μM, which is comparable with to limits of detection of the described versions of instrumental determination. The proposed colorimetric methods for determining adrenaline can be used for the quality control of medicinal products.</p>","PeriodicalId":606,"journal":{"name":"Journal of Analytical Chemistry","volume":"81 :","pages":"1354 - 1363"},"PeriodicalIF":1.5000,"publicationDate":"2026-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Analytical Chemistry","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1134/S1061934826700681","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Carbon nanodots (CNDs) of an average size of 2.7 ± 0.1 nm, exhibiting intense luminescence at 465 nm upon irradiation with a wavelength of 365 nm were synthesized from citric acid using the pyrolytic method. It was shown that, in the presence of the oxidized form of adrenaline, absorbing light at 365 nm, a noticeable quenching of the luminescence of CNDs was observed, which can be used for the luminescence determination of adrenaline. As CNDs are characterized by luminescence in the visible spectral region, both visual and colorimetric (using a camera and a smartphone camera) determination of adrenaline is possible; the achieved limit of detection is 0.8 μM, which is comparable with to limits of detection of the described versions of instrumental determination. The proposed colorimetric methods for determining adrenaline can be used for the quality control of medicinal products.
期刊介绍：
The Journal of Analytical Chemistry is an international peer reviewed journal that covers theoretical and applied aspects of analytical chemistry; it informs the reader about new achievements in analytical methods, instruments and reagents. Ample space is devoted to problems arising in the analysis of vital media such as water and air. Consideration is given to the detection and determination of metal ions, anions, and various organic substances. The journal welcomes manuscripts from all countries in the English or Russian language.
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