Pregnancy outcomes among women with systemic lupus erythematosus in Aotearoa/New Zealand.

IF 0.7 Q4 OBSTETRICS & GYNECOLOGY

Obstetric Medicine Pub Date : 2026-08-20 DOI:10.1177/1753495X261474606

Douglas White, Zhaochu Geng, Nikki Tugnet, May Ching Soh, Chunhuan Lao

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引用次数: 0

Abstract

Aims: To describe pregnancy outcomes in those with systemic lupus erythematosus (SLE) in Aotearoa/New Zealand.

Methods: We conducted a retrospective population-based cohort study using linked national datasets from 2005 to 2022. Multivariable logistic regression estimated associations between birth outcomes and timing of SLE diagnosis, end-stage kidney disease (ESKD), ethnicity, maternal age, deprivation quintile and year of parturition.

Results: Among 2450 females with SLE, 1532 were aged 18-45 years. There were 971 births, with a live birth rate of 96.1%. Preterm birth occurred in 19.3%, caesarean section in 36.6%, and induction in 48.1%. Births occurring after the diagnosis of SLE were associated with higher odds of preterm birth (OR 1.77, 95%CI 1.17-2.71), induction (OR 2.21, 95%CI 1.58-3.11) and ESKD (OR 23.7, 95%CI 4.05-450).

Conclusions: SLE is associated with increased obstetric risk in New Zealand, particularly for pregnancies after diagnosis, and among those with ESKD, with trends toward higher risk in Māori and Pacific ethnicities.

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澳大利亚/新西兰系统性红斑狼疮妇女的妊娠结局

目的：描述新西兰Aotearoa地区系统性红斑狼疮（SLE）患者的妊娠结局。方法：我们使用2005年至2022年的相关国家数据集进行了一项基于人群的回顾性队列研究。多变量logistic回归估计了出生结果与SLE诊断时间、终末期肾病（ESKD）、种族、产妇年龄、剥夺五分位数和分娩年份之间的关联。结果：2450例SLE女性患者中，年龄在18-45岁的1532例。共有971名婴儿出生，活产率为96.1%。早产占19.3%，剖腹产占36.6%，引产占48.1%。SLE诊断后分娩与早产（OR 1.77, 95%CI 1.17-2.71）、诱发（OR 2.21, 95%CI 1.58-3.11）和ESKD （OR 23.7, 95%CI 4.05-450）的几率较高相关。结论：SLE与新西兰的产科风险增加有关，特别是诊断后怀孕，在ESKD患者中，Māori和太平洋种族的风险趋势更高。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Obstetric Medicine OBSTETRICS & GYNECOLOGY-

CiteScore

1.90

自引率

0.00%

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