Incidence Trends and Disease Burden of Vascular Intestinal Disorders: A Population-Based Study in China and Worldwide from 1990 to 2021.

IF 3.2 Q2 PERIPHERAL VASCULAR DISEASE

Vascular Health and Risk Management Pub Date : 2026-08-15 eCollection Date: 2026-01-01 DOI:10.2147/VHRM.S609512

Lanhui Zeng, Bowen Li, Junhui Gao, Suwei He, Ling Huang

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引用次数: 0

Abstract

Purpose: Vascular intestinal disorders (VID), characterized by inadequate intestinal perfusion, lead to severe complications like tissue ischemia, infarction, and inflammation. This study evaluates global and Chinese VID trends and burden from 1990 to 2021 using Global Burden of Disease (GBD) 2021 data.

Methods: Age-standardized incidence, prevalence, mortality, and disability-adjusted life years (DALYs) were extracted. Joinpoint regression analyzed temporal trends, computing average annual percentage changes (AAPC) and 95% confidence intervals. Subgroup analyses covered age, sex, and socio-demographic index.

Results: Globally, the age-standardized incidence rate (ASIR) declined from 18.81 to 15.98 per 100,000 (AAPC: -0.52%); in China, it fell from 5.92 to 5.03 (AAPC: -0.50%). However, China's absolute cases nearly doubled due to demographic shifts. Significant gender and age disparities emerged: younger males showed higher ASIR and ASMR, while women ≥75 years had elevated morbidity and mortality.

Conclusion: Despite declining age-standardized rates, the absolute VID burden escalates globally and in China. Disparities disproportionately affect elderly women and younger males. Enhanced diagnostics, equitable access, and targeted prevention are urgent. Stakeholders must prioritize integrative VID prevention strategies within non-communicable disease frameworks to mitigate this growing concern.

查看原文本刊更多论文

血管性肠疾病的发病率趋势和疾病负担：1990年至2021年中国和世界范围内基于人群的研究

目的：血管性肠疾病（VID）以肠道灌注不足为特征，可导致严重的组织缺血、梗死、炎症等并发症。本研究使用全球疾病负担（GBD） 2021数据评估了1990年至2021年全球和中国VID趋势和负担。方法：提取年龄标准化发病率、患病率、死亡率和残疾调整生命年（DALYs）。接合点回归分析时间趋势，计算年均百分比变化（AAPC）和95%置信区间。亚组分析包括年龄、性别和社会人口指数。结果：全球范围内，年龄标准化发病率（ASIR）从18.81 / 10万下降到15.98 / 10万（AAPC: -0.52%）；中国股市从5.92跌至5.03 （AAPC: -0.50%）。然而，由于人口结构的变化，中国的绝对病例几乎翻了一番。出现了显著的性别和年龄差异：年轻男性ASIR和ASMR较高，而≥75岁的女性发病率和死亡率较高。结论：尽管年龄标准化率下降，但全球和中国的VID绝对负担仍在上升。差距对老年妇女和年轻男性的影响尤为严重。加强诊断、公平获取和有针对性的预防迫在眉睫。利益攸关方必须在非传染性疾病框架内优先考虑综合VID预防战略，以减轻这一日益严重的关切。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Vascular Health and Risk Management PERIPHERAL VASCULAR DISEASE-

CiteScore

4.20

自引率

3.40%

发文量

109

审稿时长

16 weeks

期刊介绍： An international, peer-reviewed journal of therapeutics and risk management, focusing on concise rapid reporting of clinical studies on the processes involved in the maintenance of vascular health; the monitoring, prevention, and treatment of vascular disease and its sequelae; and the involvement of metabolic disorders, particularly diabetes. In addition, the journal will also seek to define drug usage in terms of ultimate uptake and acceptance by the patient and healthcare professional.