{"title":"Disruption of the research software landscape through AI software generation","authors":"Nelson D. Medina, Joergen M. R. Kornfeld","doi":"10.1038/s41592-026-03210-x","DOIUrl":null,"url":null,"abstract":"Specialized research software has historically been costly and time-consuming to create, but large language models (LLMs) have become capable enough at code generation to fundamentally change this. We describe how LLM-assisted programming disrupts the landscape by allowing researchers to build tools without support from software engineers, illustrate this with an example built rapidly by a single LLM-assisted developer, and discuss opportunities and risks.","PeriodicalId":18981,"journal":{"name":"Nature Methods","volume":"23 9","pages":"1675-1677"},"PeriodicalIF":28.3000,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature Methods","FirstCategoryId":"99","ListUrlMain":"https://www.nature.com/articles/s41592-026-03210-x","RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
引用次数: 0
Abstract
Specialized research software has historically been costly and time-consuming to create, but large language models (LLMs) have become capable enough at code generation to fundamentally change this. We describe how LLM-assisted programming disrupts the landscape by allowing researchers to build tools without support from software engineers, illustrate this with an example built rapidly by a single LLM-assisted developer, and discuss opportunities and risks.
期刊介绍:
Nature Methods is a monthly journal that focuses on publishing innovative methods and substantial enhancements to fundamental life sciences research techniques. Geared towards a diverse, interdisciplinary readership of researchers in academia and industry engaged in laboratory work, the journal offers new tools for research and emphasizes the immediate practical significance of the featured work. It publishes primary research papers and reviews recent technical and methodological advancements, with a particular interest in primary methods papers relevant to the biological and biomedical sciences. This includes methods rooted in chemistry with practical applications for studying biological problems.