{"title":"Multimodal Deep Learning for Diabetic Retinopathy: A Survey.","authors":"Genyan Qin, Qinghua Peng, Yasha Zhou, Jun Peng, Qing Liu, Jian Xu","doi":"10.1155/joph/4612172","DOIUrl":null,"url":null,"abstract":"<p><p>Diabetic retinopathy (DR) remains a leading cause of blindness globally, driving the rapid development of automated diagnostic systems leveraging deep learning. Recent research demonstrates that multimodal deep learning models that integrate retinal images, electronic health records (EHR), and clinical text data can surpass single-modality approaches in DR screening accuracy. In this survey, we systematically review advances from the last 3 years, highlighting key models and methodologies, as well as datasets and evaluation metrics. We find multimodal approaches consistently outperform single-modality models, and often by a clear margin, and identify data scarcity, domain adaptation, and interpretability as the three main hurdles ahead.</p>","PeriodicalId":16674,"journal":{"name":"Journal of Ophthalmology","volume":"2026 ","pages":"4612172"},"PeriodicalIF":2.2000,"publicationDate":"2026-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13492048/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Ophthalmology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1155/joph/4612172","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Diabetic retinopathy (DR) remains a leading cause of blindness globally, driving the rapid development of automated diagnostic systems leveraging deep learning. Recent research demonstrates that multimodal deep learning models that integrate retinal images, electronic health records (EHR), and clinical text data can surpass single-modality approaches in DR screening accuracy. In this survey, we systematically review advances from the last 3 years, highlighting key models and methodologies, as well as datasets and evaluation metrics. We find multimodal approaches consistently outperform single-modality models, and often by a clear margin, and identify data scarcity, domain adaptation, and interpretability as the three main hurdles ahead.
期刊介绍:
Journal of Ophthalmology is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies related to the anatomy, physiology and diseases of the eye. Submissions should focus on new diagnostic and surgical techniques, instrument and therapy updates, as well as clinical trials and research findings.