Screening for potentially teratogenic medications in the hospital setting: a necessity or a luxury?

IF 2.5 Q3 PHARMACOLOGY & PHARMACY
Michael Ceulemans, Lynn Bruyninckx, Evelyne Van den Broucke, Karel Allegaert, Kristel Van Calsteren, Isabel Spriet, Charlotte Quintens
{"title":"Screening for potentially teratogenic medications in the hospital setting: a necessity or a luxury?","authors":"Michael Ceulemans, Lynn Bruyninckx, Evelyne Van den Broucke, Karel Allegaert, Kristel Van Calsteren, Isabel Spriet, Charlotte Quintens","doi":"10.1093/ijpp/riag101","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>This study assessed the frequency and type of potentially teratogenic medications administered to hospitalized pregnant women.</p><p><strong>Methods: </strong>A retrospective study was conducted among pregnant women hospitalized between 2021 and 2023.</p><p><strong>Key findings: </strong>Among 155 individuals, 1058 medications were administered (mean: 6.8 per patient), including 77 potentially teratogenic medications (7.3%), corresponding to 27.1% of the cohort. Indomethacin (18.7%), tramadol (18.1%), and sufentanil (7.7%) were most common. Such medications were used nearly twice as often during non-pregnancy versus pregnancy-related admissions (12.7% vs. 6.8%).</p><p><strong>Conclusions: </strong>The findings support the potential value of pregnancy-related monitoring, however, improving pregnancy documentation, especially in non-obstetric wards, remains essential.</p>","PeriodicalId":14284,"journal":{"name":"International Journal of Pharmacy Practice","volume":" ","pages":""},"PeriodicalIF":2.5000,"publicationDate":"2026-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Pharmacy Practice","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/ijpp/riag101","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"PHARMACOLOGY & PHARMACY","Score":null,"Total":0}
引用次数: 0

Abstract

Objectives: This study assessed the frequency and type of potentially teratogenic medications administered to hospitalized pregnant women.

Methods: A retrospective study was conducted among pregnant women hospitalized between 2021 and 2023.

Key findings: Among 155 individuals, 1058 medications were administered (mean: 6.8 per patient), including 77 potentially teratogenic medications (7.3%), corresponding to 27.1% of the cohort. Indomethacin (18.7%), tramadol (18.1%), and sufentanil (7.7%) were most common. Such medications were used nearly twice as often during non-pregnancy versus pregnancy-related admissions (12.7% vs. 6.8%).

Conclusions: The findings support the potential value of pregnancy-related monitoring, however, improving pregnancy documentation, especially in non-obstetric wards, remains essential.

在医院环境中筛查潜在致畸药物:必要还是奢侈?
目的:本研究评估了住院孕妇使用可能致畸药物的频率和类型。方法:对2021 - 2023年间住院的孕妇进行回顾性研究。主要发现:155名患者中,使用了1058种药物(平均每位患者6.8种),包括77种潜在致畸药物(7.3%),占队列的27.1%。吲哚美辛(18.7%)、曲马多(18.1%)和舒芬太尼(7.7%)最为常见。这类药物在非妊娠和妊娠相关入院期间的使用频率几乎是其两倍(12.7%对6.8%)。结论:研究结果支持妊娠相关监测的潜在价值,然而,改善妊娠记录,特别是在非产科病房,仍然是必不可少的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
2.90
自引率
5.60%
发文量
146
期刊介绍: The International Journal of Pharmacy Practice (IJPP) is a Medline-indexed, peer reviewed, international journal. It is one of the leading journals publishing health services research in the context of pharmacy, pharmaceutical care, medicines and medicines management. Regular sections in the journal include, editorials, literature reviews, original research, personal opinion and short communications. Topics covered include: medicines utilisation, medicine management, medicines distribution, supply and administration, pharmaceutical services, professional and patient/lay perspectives, public health (including, e.g. health promotion, needs assessment, health protection) evidence based practice, pharmacy education. Methods include both evaluative and exploratory work including, randomised controlled trials, surveys, epidemiological approaches, case studies, observational studies, and qualitative methods such as interviews and focus groups. Application of methods drawn from other disciplines e.g. psychology, health economics, morbidity are especially welcome as are developments of new methodologies.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书