Coherent modem-enabled spread-spectrum time-domain diffuse optical spectroscopy.

IF 3.2 2区医学 Q2 BIOCHEMICAL RESEARCH METHODS

Biomedical optics express Pub Date : 2026-07-22 eCollection Date: 2026-08-01 DOI:10.1364/BOE.601122

Jiaying Lu, Brandon Buscaino, Michael A Reimer, Mohammad E Mousa Pasandi, Kim Roberts

引用次数: 0

Abstract

We present a spread-spectrum time-domain diffuse optical spectroscopy (TD DOS) system utilizing a commercially available dual-polarization coherent optical modem operating at a wavelength of 1547.7 nm. The modem features a sampling rate of 114.6 GSa/s, enabling a temporal resolution of 17.5 ps. Our findings demonstrate that for low received optical powers (< -72 dBm), the scattering and absorption parameters of two studied tissue phantoms can be estimated with less than 12% fitting error within an exposure time of under 6 ms.

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相干调制解调器支持扩频时域漫射光谱学。

我们提出了一种扩频时域漫射光谱（TD DOS）系统，该系统利用市售的双偏振相干光调制解调器，工作波长为1547.7 nm。该调制解调器的采样率为114.6 GSa/s，时间分辨率为17.5 ps。我们的研究结果表明，在低接收光功率（< -72 dBm）的情况下，在低于6 ms的曝光时间内，可以以小于12%的拟合误差估计两种组织幻影的散射和吸收参数。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Biomedical optics express BIOCHEMICAL RESEARCH METHODS-OPTICS

CiteScore

6.80

自引率

11.80%

发文量

633

审稿时长

1 months

期刊介绍： The journal''s scope encompasses fundamental research, technology development, biomedical studies and clinical applications. BOEx focuses on the leading edge topics in the field, including: Tissue optics and spectroscopy Novel microscopies Optical coherence tomography Diffuse and fluorescence tomography Photoacoustic and multimodal imaging Molecular imaging and therapies Nanophotonic biosensing Optical biophysics/photobiology Microfluidic optical devices Vision research.