Efficacy Analysis of Evidence-Based Nursing Combined With Computer-Assisted Cognitive Correction Therapy on Cognitive Function and Quality of Life in Patients With Schizophrenia.

IF 2.1 4区医学 Q4 NEUROSCIENCES

Actas espanolas de psiquiatria Pub Date : 2026-08-15 DOI:10.62641/aep.v54i4.2325

Yinai Zhao, Xiulong Liu

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Abstract

Background: To investigate the effects of evidence-based nursing combined with computer-assisted cognitive remediation on cognitive function and quality of life in patients with schizophrenia.

Methods: A retrospective analysis was conducted on the clinical data of 120 patients with schizophrenia admitted between March 2023 and March 2025. Patients were divided into an observation group (n = 60, receiving evidencebased nursing combined with computer-assisted cognitive remediation) and a control group (n = 60, receiving routine nursing combined with routine cognitive training) according to their treatment and nursing protocols. Continuous treatment included in-hospital and post-discharge 12 weeks. Cognitive function, including the Wisconsin Card Sorting Test (WCST), Digit Symbol Substitution Test (DSST), Semantic Verbal Fluency (sVF) task, and the Schizophrenia Patient Quality of Life Scale (SQLS), was compared between the two groups before and 12 weeks after treatment.

Results: Before treatment, there were no statistically significant differences in the scores of WCST, DSST, sVF, and SQLS dimensions between the two groups (p > 0.05). After 12 weeks of treatment, all cognitive indices showed significant within-group improvements for both groups (all p < 0.001), while each SQLS dimension and total score were significantly reduced within each group (observation group: all p < 0.01; control group: all p < 0.05). After Bonferroni correction for multiple comparisons, all cognitive and SQLS outcomes showed significantly larger improvements in the observation group relative to the control group (all corrected between-group p < 0.001).

Conclusions: Evidence-based nursing combined with computer-assisted cognitive correction therapy is associated with better cognitive performance and higher quality of life in patients with schizophrenia, showing promising clinical application value.

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循证护理结合计算机辅助认知矫正治疗对精神分裂症患者认知功能和生活质量的疗效分析。

背景：探讨循证护理结合计算机辅助认知修复对精神分裂症患者认知功能和生活质量的影响。方法：回顾性分析2023年3月至2025年3月收治的120例精神分裂症患者的临床资料。根据患者的治疗和护理方案，将患者分为观察组（n = 60）和对照组（n = 60），分别接受循证护理和计算机辅助认知修复相结合的护理。持续治疗包括住院和出院后12周。比较两组治疗前和治疗后12周的认知功能，包括威斯康星卡片分类测验（WCST）、数字符号替代测验（DSST）、语义语言流畅性（sVF）任务和精神分裂症患者生活质量量表（SQLS）。结果：治疗前，两组患者WCST、DSST、sVF、SQLS维度评分比较，差异均无统计学意义（p < 0.05）。治疗12周后，两组患者各认知指标组内均有显著改善（均p < 0.001），各SQLS维度及总分组内均显著降低（观察组：均p < 0.01；对照组：均p < 0.05）。经多次比较Bonferroni校正后，观察组的所有认知和sql结果均较对照组有显著性改善（组间校正p < 0.001）。结论：循证护理结合计算机辅助认知矫正治疗可改善精神分裂症患者的认知表现和生活质量，具有良好的临床应用价值。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Actas espanolas de psiquiatria 医学-精神病学

CiteScore

1.70

自引率

6.70%

发文量

审稿时长

>12 weeks

期刊介绍： Actas Españolas de Psiquiatría publicará de manera preferente trabajos relacionados con investigación clínica en el área de la Psiquiatría, la Psicología Clínica y la Salud Mental.