Intranasal Azelastine for Recurrent Acute Rhinosinusitis Prophylaxis: A Multicenter Retrospective Study

IF 4.9 2区医学 Q1 OTORHINOLARYNGOLOGY

International Forum of Allergy & Rhinology Pub Date : 2026-10-04 Epub Date: 2026-08-14 DOI:10.1002/alr.70244

Akshay R. Prabhakar, Justina R. Varghese, William Marshall, Utkarsh Singh, Jake Hacker, Yixuan J. Zheng, Samuel E. Razmi, Ron L. Moses, Chadi A. Makary, Masayoshi Takashima, Omar G. Ahmed

引用次数: 0

Abstract

Key Points

Self-controlled analysis: mean episodes reduced from 2.72 to 1.18 per year; 56.6% reduction.
Treatment effect consistent across subgroups, from patients using intranasal corticosteroids (ICS) to those with concurrent chronicc rhinosinusitis (CRS).
Findings support prospective randomized controlled trial evaluation of azelastine for recurrent acute rhinosinusitis (RARS).

查看原文本刊更多论文

鼻用氮唑elastine预防复发性急性鼻窦炎：一项多中心回顾性研究。

自我控制分析：平均发作次数从2.72次/年减少到1.18次/年；减少56.6%。从使用鼻内皮质类固醇（ICS）的患者到并发慢性鼻窦炎（CRS）的患者，整个亚组的治疗效果一致。研究结果支持前瞻性随机对照试验评价azelastine治疗复发性急性鼻窦炎（RARS）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Forum of Allergy & Rhinology OTORHINOLARYNGOLOGY-

CiteScore

11.70

自引率

10.90%

发文量

185

审稿时长

6-12 weeks

期刊介绍： International Forum of Allergy & Rhinologyis a peer-reviewed scientific journal, and the Official Journal of the American Rhinologic Society and the American Academy of Otolaryngic Allergy. International Forum of Allergy Rhinology provides a forum for clinical researchers, basic scientists, clinicians, and others to publish original research and explore controversies in the medical and surgical treatment of patients with otolaryngic allergy, rhinologic, and skull base conditions. The application of current research to the management of otolaryngic allergy, rhinologic, and skull base diseases and the need for further investigation will be highlighted.