The Potential of Spatially Detecting SPIONs Using Multiple Sensor Coils

IF 2.5 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC

IEEE Transactions on Molecular, Biological, and Multi-Scale Communications Pub Date : 2026-01-01 Epub Date: 2026-08-05 DOI:10.1109/TMBMC.2026.3720580

Paul Wolff;Luiz C. P. Wille;Stefan Lyer;Jens Kirchner

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引用次数: 0

Abstract

Detecting magnetic nanoparticles with inductive sensor coils is a proven, feasible and cost-efficient method. Recently, molecular communication in fluids, primarily vascular system models, has been investigated. The one-sensor approach is useful for determining the presence of superparamagnetic iron-oxide nanoparticles (SPIONs) in the vicinity of the sensor. However, distinguishing between a small number of particles close to the sensor and a greater number further away remains problematic. To solve this, spatial detection using multiple sensors is investigated. This opens up the possibility of utilizing spatial information in a communication context, as well as enabling imaging options that display the particle distribution over the cross-sectional area of the channel. In consequence, the concentration can be determined with greater precision. The stability of the sensors is investigated, proving the reliability of reference scales for the shift to concentration relation. Nonetheless, the presented approach is subject to several limitations and factors that must be considered in future work. To conclude the presented work, it can be said that advances could be achieved in the position and concentration determination of SPIONs, as well as a structured investigation on sensor stability.

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多传感器线圈空间探测SPIONs的潜力

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来源期刊

IEEE Transactions on Molecular, Biological, and Multi-Scale Communications Mathematics-Modeling and Simulation

CiteScore

3.90

自引率

13.60%

发文量

期刊介绍： As a result of recent advances in MEMS/NEMS and systems biology, as well as the emergence of synthetic bacteria and lab/process-on-a-chip techniques, it is now possible to design chemical “circuits”, custom organisms, micro/nanoscale swarms of devices, and a host of other new systems. This success opens up a new frontier for interdisciplinary communications techniques using chemistry, biology, and other principles that have not been considered in the communications literature. The IEEE Transactions on Molecular, Biological, and Multi-Scale Communications (T-MBMSC) is devoted to the principles, design, and analysis of communication systems that use physics beyond classical electromagnetism. This includes molecular, quantum, and other physical, chemical and biological techniques; as well as new communication techniques at small scales or across multiple scales (e.g., nano to micro to macro; note that strictly nanoscale systems, 1-100 nm, are outside the scope of this journal). Original research articles on one or more of the following topics are within scope: mathematical modeling, information/communication and network theoretic analysis, standardization and industrial applications, and analytical or experimental studies on communication processes or networks in biology. Contributions on related topics may also be considered for publication. Contributions from researchers outside the IEEE’s typical audience are encouraged.