Unlocking the value of cloning for wildlife conservation with research priorities, open collaborations, data/information sharing, and ethics as keys to success.

IF 2.1
Elena Ruggeri, Andres Gambini, Cesare Galli, Gabriela Mastromonaco, Pierre Comizzoli
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Abstract

Somatic cell nuclear transfer (SCNT, or cloning) in wild animal species is considered a potential tool in biodiversity conservation to restore genetic diversity in animal populations and overcome the detrimental effects of inbreeding, climate change, or diseases in rare and endangered animal populations. In January 2026, the Committee for Companion Animals, Non-Domestic and Endangered Species (CANDES) of the International Embryo Technology Society (IETS) organized a round table discussion on future directions in wildlife cloning. This paper reflects the content of discussions among experts in assisted reproductive technologies (ARTs) and specialists in wild animal conservation. After reviewing the advantages and limitations of SCNT, several research priorities were identified. Importantly, strengthening open communication and data exchange among experts was highly recommended to ensure that progress in the field is effective. It was also emphasized that regulatory and ethical frameworks are still required to better integrate this technology into animal conservation efforts. Overall, SCNT remains a highly specialized technology with a distinct, yet currently limited, role in biodiversity conservation. Its true value does not lie in immediate population recovery, but in its capacity to preserve genetic material, generate critical scientific insight, and inspire new collaborations across different disciplines.

通过优先研究、开放合作、数据/信息共享和道德规范,释放克隆对野生动物保护的价值,并以此作为成功的关键。
野生动物体细胞核移植(SCNT,或克隆)被认为是生物多样性保护的潜在工具,可以恢复动物种群的遗传多样性,克服近亲繁殖、气候变化或疾病对珍稀和濒危动物种群的不利影响。2026年1月,国际胚胎技术学会(IETS)的伴侣动物、非家养和濒危物种委员会(CANDES)组织了一次关于野生动物克隆未来方向的圆桌讨论。本文反映了辅助生殖技术专家和野生动物保护专家之间的讨论内容。在回顾了SCNT的优点和局限性之后,确定了几个研究重点。重要的是,强烈建议加强专家之间的公开沟通和数据交换,以确保该领域的进展是有效的。会议还强调,为了更好地将这项技术纳入动物保护工作,仍然需要监管和道德框架。总的来说,SCNT仍然是一项高度专业化的技术,在生物多样性保护中具有独特的作用,但目前的作用有限。它的真正价值不在于立即恢复种群数量,而在于它能够保存遗传物质,产生关键的科学见解,并激发不同学科之间的新合作。
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