Gabriel de Toledo Telles-Araujo, Raimundo Sales de Oliveira Neto, Mariana Quirino Silveira Soares, Heitor Marques Honório, Viviane Almeida Sarmento, Marco Antônio Hungaro Duarte, Izabel Regina Fischer Rubira-Bullen
{"title":"Advancing endodontic imaging: a high-resolution comparison between CBCT and micro-CT in the danger zone.","authors":"Gabriel de Toledo Telles-Araujo, Raimundo Sales de Oliveira Neto, Mariana Quirino Silveira Soares, Heitor Marques Honório, Viviane Almeida Sarmento, Marco Antônio Hungaro Duarte, Izabel Regina Fischer Rubira-Bullen","doi":"10.2340/biid.v13.46618","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>This study evaluated the accuracy of cone-beam computed tomography (CBCT) protocols for measuring submillimetric dentin thickness in the danger zone (DZ) of mandibular molars, using micro-computed tomography (micro-CT) as the reference standard.</p><p><strong>Materials and methods: </strong>Fifty-one extracted mandibular molars were scanned using micro-CT and two CBCT devices under different acquisition protocols (Standard, High Fidelity, High Resolution [HIRE], and Imaging System [i-CAT]). After three-dimensional image registration, dentin thickness in the DZ, located 2 mm below the furcation, was measured in both mesial canals.</p><p><strong>Results: </strong>All CBCT protocols significantly underestimated dentin thickness compared with micro-CT (<i>p</i> < 0.05), with discrepancies ranging from 4.5 to 8.6%. Underestimation was more pronounced in the mesiolingual canal. The HIRE protocol (0.125 mm voxel size) showed the smallest discrepancy, whereas the i-CAT protocol showed the largest.</p><p><strong>Conclusions: </strong>CBCT systematically underestimates dentin thickness in the DZ and is not metrically equivalent to micro-CT for submillimetric measurements. Measurement accuracy is influenced by acquisition parameters and cannot be explained by voxel size alone.</p>","PeriodicalId":72378,"journal":{"name":"Biomaterial investigations in dentistry","volume":"13 ","pages":"46618"},"PeriodicalIF":0.0000,"publicationDate":"2026-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13454917/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomaterial investigations in dentistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2340/biid.v13.46618","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2026/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: This study evaluated the accuracy of cone-beam computed tomography (CBCT) protocols for measuring submillimetric dentin thickness in the danger zone (DZ) of mandibular molars, using micro-computed tomography (micro-CT) as the reference standard.
Materials and methods: Fifty-one extracted mandibular molars were scanned using micro-CT and two CBCT devices under different acquisition protocols (Standard, High Fidelity, High Resolution [HIRE], and Imaging System [i-CAT]). After three-dimensional image registration, dentin thickness in the DZ, located 2 mm below the furcation, was measured in both mesial canals.
Results: All CBCT protocols significantly underestimated dentin thickness compared with micro-CT (p < 0.05), with discrepancies ranging from 4.5 to 8.6%. Underestimation was more pronounced in the mesiolingual canal. The HIRE protocol (0.125 mm voxel size) showed the smallest discrepancy, whereas the i-CAT protocol showed the largest.
Conclusions: CBCT systematically underestimates dentin thickness in the DZ and is not metrically equivalent to micro-CT for submillimetric measurements. Measurement accuracy is influenced by acquisition parameters and cannot be explained by voxel size alone.