Evidence for the multistage malaria vaccine gamble.

IF 7.6 1区医学 Q1 PARASITOLOGY

Trends in parasitology Pub Date : 2026-09-01 Epub Date: 2026-08-11 DOI:10.1016/j.pt.2026.07.014

Chester J Joyner, Amadis R Vivas, Wayne T Cheng

引用次数: 0

Abstract

New vaccines to reduce disease and mortality caused by Plasmodium falciparum malaria are urgently needed. Most vaccines target a single life-cycle stage and confer modest protection. Kirtley et al. test whether multistage immunity can improve protection and provide some of the first evidence that 'multistage' vaccines should be pursued.

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多阶段疟疾疫苗赌博的证据。

迫切需要新的疫苗，以减少由恶性疟原虫疟疾引起的疾病和死亡率。大多数疫苗针对单一生命周期阶段，并提供适度的保护。Kirtley等人测试了多阶段免疫是否能提高保护作用，并提供了应该研制“多阶段”疫苗的一些初步证据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Trends in parasitology 医学-寄生虫学

CiteScore

14.00

自引率

3.10%

发文量

148

审稿时长

6-12 weeks

期刊介绍： Since its inception as Parasitology Today in 1985, Trends in Parasitology has evolved into a highly esteemed review journal of global significance, reflecting the importance of medical and veterinary parasites worldwide. The journal serves as a hub for communication among researchers across all disciplines of parasitology, encompassing endoparasites, ectoparasites, transmission vectors, and susceptible hosts. Each monthly issue of Trends in Parasitology offers authoritative, cutting-edge, and yet accessible review articles, providing a balanced and comprehensive overview, along with opinion pieces offering personal and novel perspectives. Additionally, the journal publishes a variety of short articles designed to inform and stimulate thoughts in a lively and widely-accessible manner. These include Science & Society (discussing the interface between parasitology and the general public), Spotlight (highlighting recently published research articles), Forum (presenting single-point hypotheses), Parasite/Vector of the Month (featuring a modular display of the selected species), Letter (providing responses to recent articles in Trends in Parasitology), and Trendstalk (conducting interviews). Please note that the journal exclusively publishes literature reviews based on published data, with systematic reviews, meta-analysis, and unpublished primary research falling outside our scope.