Impact of air quality on tissue eosinophilia and clinical severity of chronic rhinosinusitis.

IF 5.7 2区医学 Q1 OTORHINOLARYNGOLOGY

Rhinology Pub Date : 2026-08-11 DOI:10.4193/Rhin26.324

A Q Le, T Tran, J Samuthpongtorn, K Seresirikachorn, W Chitsuthipakorn, M P Hoang, L V Tran, M T Q Le, S Chusakul, J Kanchanaumporn, P Wungcharoen, K Snidvongs

引用次数: 0

Abstract

Particulate matter 2.5 (PM2.5) exposure impairs nasal epithelial defenses, disrupts mucociliary clearance, increases oxidative stress, and exacerbates inflammatory pathways associated with chronic rhinosinusitis (CRS). While it impacts upper airway diseases, the relationship between PM2.5 exposure and eosinophilic CRS (ECRS) with tissue eosinophil >10 cells/ HPF remains unclear. A cross-sectional study was conducted in Thailand and Vietnam to investigate the impact of PM2.5 exposure on tissue eosinophilia and the severity of CRS.

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空气质量对慢性鼻窦炎嗜酸性粒细胞增多和临床严重程度的影响。

颗粒物2.5 （PM2.5）暴露会损害鼻上皮防御，破坏粘膜纤毛清除，增加氧化应激，并加剧与慢性鼻窦炎（CRS）相关的炎症途径。虽然它影响上呼吸道疾病，但PM2.5暴露与嗜酸性粒细胞CRS （ECRS）与组织嗜酸性粒细胞10细胞/ HPF之间的关系尚不清楚。在泰国和越南进行了一项横断面研究，以调查PM2.5暴露对组织嗜酸性粒细胞增多和CRS严重程度的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Rhinology 医学-耳鼻喉科学

CiteScore

15.80

自引率

9.70%

发文量

135

审稿时长

6-12 weeks

期刊介绍： Rhinology serves as the official Journal of the International Rhinologic Society and is recognized as one of the journals of the European Rhinologic Society. It offers a prominent platform for disseminating rhinologic research, reviews, position papers, task force reports, and guidelines to an international scientific audience. The journal also boasts the prestigious European Position Paper in Rhinosinusitis (EPOS), a highly influential publication first released in 2005 and subsequently updated in 2007, 2012, and most recently in 2020. Employing a double-blind peer review system, Rhinology welcomes original articles, review articles, and letters to the editor.