An all-hydrogel fiber neural electrode array shrinks to the scale of neurons

Abstract

The chronic performance of implantable neural electrodes is often compromised by multidimensional mismatches with living brain tissue, including geometric size, mechanical compliance, three-dimensional topology, and biochemical properties. Here, this preview highlights a study by Wang et al. that shrinks all-hydrogel fiber electrodes to the scale of neurons, advancing tissue-matched neural interfaces for stable long-term recording with minimal immune response.