{"title":"Frequency of exercise and cancer-related fatigue among patients with lymphoma.","authors":"Shintaro Inoue, Kenta Kawamitsu, Shota Okuno, Tsubasa Yokote, Kengo Shirado, Junichi Kiyasu","doi":"10.1038/s44276-026-00246-6","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Exercise is recognized for its efficacy in alleviating cancer-related fatigue (CRF). However, the effect of high-frequency exercise on CRF has not been clarified. This study aimed to elucidate the association between exercise frequency during hospitalization and CRF in patients with lymphoma.</p><p><strong>Methods: </strong>This retrospective study included patients with lymphoma admitted for chemotherapy who were advised to engage in aerobic and resistance training once daily, six days per week. Exercise frequency was calculated as the percentage of hospitalization days during which therapy was administered. Participants were categorized into two groups based on exercise frequency. CRF was evaluated using the Cancer Fatigue Scale (CFS), comprising 15 items that assess physical, affective, and cognitive factors.</p><p><strong>Results: </strong>A total of 130 patients (median age: 72 [range: 66 -78] years) were eligible to participate. The median frequency of exercise was 71.4%. Multiple regression analysis revealed that the exercise frequency significantly affected the physical CFS score at discharge. However, no statistically significant relationship was observed between exercise participation frequency and other CFS scores.</p><p><strong>Conclusions: </strong>Higher-frequency exercise was significantly associated with a reduction in CRF at discharge.</p>","PeriodicalId":519964,"journal":{"name":"BJC reports","volume":"4 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2026-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13451409/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"BJC reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1038/s44276-026-00246-6","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Exercise is recognized for its efficacy in alleviating cancer-related fatigue (CRF). However, the effect of high-frequency exercise on CRF has not been clarified. This study aimed to elucidate the association between exercise frequency during hospitalization and CRF in patients with lymphoma.
Methods: This retrospective study included patients with lymphoma admitted for chemotherapy who were advised to engage in aerobic and resistance training once daily, six days per week. Exercise frequency was calculated as the percentage of hospitalization days during which therapy was administered. Participants were categorized into two groups based on exercise frequency. CRF was evaluated using the Cancer Fatigue Scale (CFS), comprising 15 items that assess physical, affective, and cognitive factors.
Results: A total of 130 patients (median age: 72 [range: 66 -78] years) were eligible to participate. The median frequency of exercise was 71.4%. Multiple regression analysis revealed that the exercise frequency significantly affected the physical CFS score at discharge. However, no statistically significant relationship was observed between exercise participation frequency and other CFS scores.
Conclusions: Higher-frequency exercise was significantly associated with a reduction in CRF at discharge.
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