Beyond axial length: posterior segment curvature determining vitreoretinal traction.

IF 2.1 2区医学 Q2 OPHTHALMOLOGY

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2026-08-07 DOI:10.1097/IAE.0000000000004959

João Heitor Marques, Ana Sofia Martins, Pedro Baptista, Bernardete Pessoa, João Melo Beirão

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引用次数: 0

Abstract

Purpose: To create an algorithm to calculate the posterior radius of curvature of Bruch´s membrane (rBM) on regular optical coherence tomography (OCT) and determine the association between posterior segment shape and vitreoretinal disease.

Methods: Retrospective cross-sectional study that included patients with macular hole (MH) or rhegmatogenous retinal detachment (RRD). RRD eyes were matched with MH eyes based on age and axial length (AL), resulting in a final analysis of 43 eyes in each group. OCT B-scans were processed using a custom but open algorithm to calculate the rBM.

Results: rBM was significantly higher in the RRD group (mean 56.1 mm, 95%CI 46.2 - 66.1 mm) whereas the MH group exhibited a steeper curvature (mean 41.6 mm, 95%CI 37.4 - 45.9 mm). No relationship was observed between AL and rBM. Multivariate logistic regression confirmed the independent effect of rBM.

Conclusion: The geometry of the posterior segment differs substantially, independently of AL and age. A rounder posterior segment is associated with RRD, while a steeper curvature is associated with MH, suggesting that globe shape dictates whether vitreoretinal traction manifests peripherally or centrally. rBM on OCT is a simple and reproducible measure that may serve as a risk factor for vitreoretinal disease.

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轴外长度：决定玻璃体视网膜牵引力的后节曲率。

目的：建立一种计算常规光学相干断层扫描（OCT） Bruch’s膜（rBM）后曲率半径的算法，确定后段形状与玻璃体视网膜疾病的关系。方法：回顾性横断面研究纳入黄斑孔（MH）或孔源性视网膜脱离（RRD）患者。根据年龄和轴长（AL）将RRD眼与MH眼进行匹配，每组43只眼进行最终分析。OCT b扫描使用自定义但开放的算法来计算rBM。结果：RRD组rBM明显增高（平均56.1 mm, 95%CI 46.2 ~ 66.1 mm），而MH组rBM更陡（平均41.6 mm, 95%CI 37.4 ~ 45.9 mm）。AL与rBM之间无相关性。多因素logistic回归证实了rBM的独立作用。结论：后节段的几何形状有很大的不同，与AL和年龄无关。较圆的后段与RRD有关，而较陡的曲率与MH有关，这表明球体形状决定了玻璃体视网膜牵引力是表现在周围还是中央。OCT上的rBM是一种简单且可重复的测量方法，可以作为玻璃体视网膜疾病的危险因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Retina-The Journal of Retinal and Vitreous Diseases 医学-眼科学

CiteScore

5.70

自引率

9.10%

发文量

554

审稿时长

3-6 weeks

期刊介绍： RETINA® focuses exclusively on the growing specialty of vitreoretinal disorders. The Journal provides current information on diagnostic and therapeutic techniques. Its highly specialized and informative, peer-reviewed articles are easily applicable to clinical practice. In addition to regular reports from clinical and basic science investigators, RETINA® publishes special features including periodic review articles on pertinent topics, special articles dealing with surgical and other therapeutic techniques, and abstract cards. Issues are abundantly illustrated in vivid full color. Published 12 times per year, RETINA® is truly a “must have” publication for anyone connected to this field.