Charge-cloud-based micrometer resolution in deep-silicon photon-counting CT.

IF 2.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Journal of Medical Imaging Pub Date : 2026-07-01 Epub Date: 2026-08-06 DOI:10.1117/1.JMI.13.4.043501
Rickard Brunskog, Mats Persson, Moa Yveborg Tamm, Umberto Follo, Mats Danielsson
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引用次数: 0

Abstract

Purpose: We are developing a monolithic deep-silicon photon-counting sensor targeting spatial resolution on the order of 1    μ m . This work investigates how pixel pitch, noise level, threshold number, and threshold placement affect the achievable tangential and wafer-thickness resolution to guide the CMOS electronics and sensor design.

Approach: Allpix Squared simulations were used to evaluate pixel pitches with two noise levels and two threshold-placement schemes over varying threshold numbers. Interaction position was estimated in both dimensions using lookup tables trained on the thresholded pixel output, and performance was quantified using the MTF.

Results: Decreasing pixel pitch strongly improved tangential resolution for Compton interactions, whereas photoelectric interactions showed a weaker dependence on pixel pitch and threshold placement. Equal-counting thresholds approached the achievable resolution with fewer thresholds than equidistant thresholds. For eight equal-counting thresholds, the 10% MTF across the studied pixel sizes ranged from 1284   lp / cm to 2452   lp / cm in the tangential direction and from 15 to 71    lp / cm in the wafer-thickness direction for Compton interactions, compared with 409 to 507    lp / cm and 18 to 79    lp / cm , respectively, for photoelectric interactions. RMSE analysis further showed that some interactions for the 25    μ m pitch reached below 2    μ m tangentially and a few tens of micrometers in the wafer-thickness direction.

Conclusions: Spatial resolution improved with a threshold number up to about 8 to 10, beyond which additional programmable thresholds gave only modest gain. The achieved tangential resolution also suggests that analyzer-free phase-contrast imaging is feasible for realistic geometries and expected interference patterns.

深硅光子计数CT中基于电荷云的微米分辨率。
目的:我们正在开发一种单片深硅光子计数传感器,目标空间分辨率为1 μ m。本文研究了像素间距、噪声水平、阈值数量和阈值位置如何影响可实现的切向分辨率和晶圆厚度分辨率,以指导CMOS电子和传感器设计。方法:使用Allpix Squared模拟来评估具有两种噪声水平和两种阈值放置方案的不同阈值数的像素间距。使用在阈值像素输出上训练的查找表在两个维度上估计交互位置,并使用MTF对性能进行量化。结果:降低像素间距可显著提高康普顿相互作用的切向分辨率,而光电相互作用对像素间距和阈值位置的依赖性较弱。等计数阈值比等距阈值更接近可实现的分辨率。对于8个等计数阈值,康普顿相互作用的10% MTF在切向范围为1284 lp / cm至2452 lp / cm,在晶圆厚度方向范围为15至71 lp / cm,而光电相互作用的10% MTF分别为409至507 lp / cm和18至79 lp / cm。RMSE分析进一步表明,25 μ m间距的一些相互作用在切向上达到2 μ m以下,在晶圆厚度方向上达到几十微米。结论:空间分辨率随着阈值增加到8到10而提高,超过这个阈值,额外的可编程阈值只会带来适度的增益。所取得的切向分辨率也表明,无分析仪相衬成像是可行的实际几何形状和预期的干涉模式。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Medical Imaging
Journal of Medical Imaging RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
4.10
自引率
4.20%
发文量
0
期刊介绍: JMI covers fundamental and translational research, as well as applications, focused on medical imaging, which continue to yield physical and biomedical advancements in the early detection, diagnostics, and therapy of disease as well as in the understanding of normal. The scope of JMI includes: Imaging physics, Tomographic reconstruction algorithms (such as those in CT and MRI), Image processing and deep learning, Computer-aided diagnosis and quantitative image analysis, Visualization and modeling, Picture archiving and communications systems (PACS), Image perception and observer performance, Technology assessment, Ultrasonic imaging, Image-guided procedures, Digital pathology, Biomedical applications of biomedical imaging. JMI allows for the peer-reviewed communication and archiving of scientific developments, translational and clinical applications, reviews, and recommendations for the field.
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