Medicare Advantage and Access to Living Donor Kidney Transplantation among Older Patients Receiving Dialysis.

IF 9.7 1区 医学 Q1 UROLOGY & NEPHROLOGY
Joel T Adler, Arnold E Kuk, Kelsey M Drewry, Kevin H Nguyen, Katherine Ross-Driscoll, Adam Bingaman, Stephen O Pastan, Adam S Wilk
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引用次数: 0

Abstract

Key points: Medicare Advantage was associated with lower kidney transplant waitlisting among older adults initiating dialysis. After waitlisting, Medicare Advantage was associated with lower living donor kidney transplantation but not deceased donor transplantation. Findings suggest payer-related barriers may differ across transplant pathway steps and living donor processes.

Background: Medicare Advantage enrollment is rising among older adults with kidney failure. Compared with traditional Medicare, the contracted provider networks and utilization management of Medicare Advantage may introduce friction in transplant evaluation and living donor coordination, potentially restricting access for vulnerable beneficiaries. We examined whether Medicare Advantage is associated with access to living donor kidney transplantation and whether associations vary by rurality, age, or county-level social vulnerability.

Methods: Using the United States Renal Data System, we identified adults aged 65-80 years initiating dialysis in 2015-2021 with follow-up through March 15, 2024 ( N =284,166; analytic N =279,229 with complete covariate data). Payer was classified at day 90 after dialysis initiation for waitlisting and overall incident-cohort models and at waitlisting for postwaitlisting transplant models. Fine-Gray competing risks models estimated subdistribution hazard ratios (sHRs) for time to waitlisting (death as the competing event) and, among waitlisted patients, time to any transplantation (death and delisting as competing events) and to deceased donor kidney transplantation or living donor kidney transplantation (death, delisting, and receipt of the alternate donor type as competing events). We adjusted for demographics, dual eligibility, clinical factors, rurality, and county-level Social Vulnerability Index quartiles.

Results: Forty-two percent were enrolled in Medicare Advantage. Among 279,229 patients in adjusted models, 15,664 (6%) were waitlisted. Medicare Advantage was associated with lower likelihood of waitlisting versus traditional Medicare (sHR, 0.87; 95% confidence interval [CI], 0.84 to 0.90). Among waitlisted patients, Medicare Advantage was not associated with the incidence of any kidney transplantation (sHR, 0.99; 95% CI, 0.94 to 1.03) or deceased donor kidney transplantation (sHR, 1.04; 95% CI, 0.99 to 1.10) but was associated with a lower incidence of living donor kidney transplantation (sHR, 0.85; 95% CI, 0.77 to 0.94).

Conclusions: Among older adults with kidney failure initiating dialysis, Medicare Advantage was associated with lower waitlisting and lower living donor kidney transplantation after waitlisting but was not associated with deceased donor kidney transplantation or any kidney transplantation after waitlisting.

老年透析患者接受活体肾移植的医疗保险优势和可及性。
背景:老年肾衰竭患者的医疗保险优惠登记人数正在上升。与传统医疗保险相比,“医保优势”的签约提供者网络和使用管理可能会在移植评估和活体供体协调方面产生摩擦,可能会限制弱势受益人的获取。我们研究了医疗保险优势是否与获得活体供体肾移植有关,以及这种联系是否因农村地区、年龄或县级社会脆弱性而异。方法:使用美国肾脏数据系统,我们确定了2015-2021年开始透析的65-80岁的成年人,随访至2024年3月15日(N=284,166;分析N=279,229,完整协变量数据)。患者在透析开始后第90天被分类为等待列表和总体事件队列模型,在等待列表后移植模型中被分类为等待列表。细灰色竞争风险模型估计了等待名单时间(死亡作为竞争事件)、等待名单患者中进行任何移植(死亡和被除名作为竞争事件)和死亡供体肾脏移植或活体肾脏移植(死亡、被除名和接受替代供体类型作为竞争事件)的亚分布风险比(sHRs)。我们调整了人口统计学、双重资格、临床因素、乡村性和县级社会脆弱性指数四分位数。结果:42%的人参加了医疗保险优惠计划。在调整模型的279,229例患者中,15,664例(6%)患者被列入等待名单。与传统医疗保险相比,医疗保险优势与更低的等待名单可能性相关(sHR 0.87, 95% CI 0.84-0.90)。在等候名单患者中,Medicare Advantage与任何肾移植(sHR 0.99, 95% CI 0.94-1.03)或已故供体肾移植(sHR 1.04, 95% CI 0.99-1.10)的发生率无关,但与活体供体肾移植的发生率较低相关(sHR 0.85, 95% CI 0.77-0.94)。结论:在开始透析的肾衰竭老年人中,医疗保险优势与等待名单和等待名单后活体供体肾移植的减少有关,但与死亡供体肾移植或等待名单后的任何肾移植无关。
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来源期刊
Journal of The American Society of Nephrology
Journal of The American Society of Nephrology 医学-泌尿学与肾脏学
CiteScore
22.40
自引率
2.90%
发文量
492
审稿时长
3-8 weeks
期刊介绍: The Journal of the American Society of Nephrology (JASN) stands as the preeminent kidney journal globally, offering an exceptional synthesis of cutting-edge basic research, clinical epidemiology, meta-analysis, and relevant editorial content. Representing a comprehensive resource, JASN encompasses clinical research, editorials distilling key findings, perspectives, and timely reviews. Editorials are skillfully crafted to elucidate the essential insights of the parent article, while JASN actively encourages the submission of Letters to the Editor discussing recently published articles. The reviews featured in JASN are consistently erudite and comprehensive, providing thorough coverage of respective fields. Since its inception in July 1990, JASN has been a monthly publication. JASN publishes original research reports and editorial content across a spectrum of basic and clinical science relevant to the broad discipline of nephrology. Topics covered include renal cell biology, developmental biology of the kidney, genetics of kidney disease, cell and transport physiology, hemodynamics and vascular regulation, mechanisms of blood pressure regulation, renal immunology, kidney pathology, pathophysiology of kidney diseases, nephrolithiasis, clinical nephrology (including dialysis and transplantation), and hypertension. Furthermore, articles addressing healthcare policy and care delivery issues relevant to nephrology are warmly welcomed.
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